Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.56 |
| ▸ | AGTR2 | P50052 | 8/20 | 0.53 |
| ▸ | AGTR1 | P30556 | 8/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8172767 | 0.95 | GP6 (0.63) | GP6AGTR2AGTR1 | |
| SCHEMBL976 | 0.91 | GP6 (0.64) | GP6AGTR2AGTR1 | |
| SCHEMBL7175115 | 0.86 | AGTR2 (0.49) | GP6AGTR2AGTR1 | |
| SCHEMBL6536653 | 0.86 | AGTR1 (0.57) | AGTR2AGTR1 | |
| SCHEMBL860 | 0.86 | GP6 (0.72) | GP6AGTR2AGTR1 | |
| SCHEMBL7362569 | 0.84 | AGTR2 (0.72) | GP6AGTR2AGTR1 | |
| SCHEMBL8469323 | 0.82 | AGTR1 (0.46) | AGTR2AGTR1 | |
| SCHEMBL9198036 | 0.81 | AGTR2 (0.58) | GP6AGTR2AGTR1 | |
| SCHEMBL9030299 | 0.81 | AGTR2 (0.56) | GP6AGTR2AGTR1 | |
| SCHEMBL3427175 | 0.81 | AGTR1 (0.64) | AGTR2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019048-A1 | USE OF AN ANGIOTENSIN II RECEPTOR ANTAGONIST FOR THE PREPARATION OF DRUGS TO INCREASE THE SURVIVAL RATE OF RENAL TRANSPLANT PATIENTS | Merck Sharp Dohme (Italia) S.P.A. (IT) | 2000-07-19 | — | — | EP | claimed |
| WO-1999016437-A1 | USE OF AN ANGIOTENSIN II RECEPTOR ANTAGONIST FOR THE PREPARATION OF DRUGS TO INCREASE THE SURVIVAL RATE OF RENAL TRANSPLANT PATIENTS | MERCK SHARP DOHME (ITALIA) S.P.A. (IT) | 1999-04-08 | — | — | WO | claimed |