Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 8/20 | 0.35 |
| ▸ | RAB9A | P51151 | 8/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 4/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.34 |
| ▸ | RELA | Q04206 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5657856 | 0.96 | CYP11B1 (0.44) | CYP11B1CYP11B2TSHRNPC1RAB9A | |
| SCHEMBL17610579 | 0.78 | NOTUM (0.48) | RAB9ASMN1; SMN2MAPT | |
| SCHEMBL8077911 | 0.76 | NPC1 (0.36) | CYP11B1CYP11B2NPC1RAB9AMEN1 | |
| SCHEMBL2794744 | 0.76 | HTR2A (0.37) | CYP11B1CYP11B2NPC1RAB9AMEN1 | |
| SCHEMBL28592057 | 0.76 | MAPT (0.47) | TSHRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL27864869 | 0.74 | KIF11 (0.34) | ALDH1A1MAPT | |
| SCHEMBL3149937 | 0.73 | PRKAB2 (0.36) | RAB9ASMN1; SMN2MAPT | |
| SCHEMBL3141306 | 0.73 | DYRK1A (0.48) | NPC1RAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL28655422 | 0.73 | CYP11B1 (0.55) | CYP11B1CYP11B2TSHRNPC1RAB9A | |
| SCHEMBL29541304 | 0.73 | CYP11B1 (0.55) | CYP11B1CYP11B2TSHRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166072-A | Amino acid derivatives | ALLELIX NEUROSCIENCE, INC. (CA) | 2000-12-26 | — | — | US | disclosed |