Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.36 |
| ▸ | RAB9A | P51151 | 8/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2794744 | 0.80 | HTR2A (0.37) | NPC1RAB9ASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL8072407 | 0.76 | CYP11B1 (0.40) | NPC1RAB9ASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL5797082 | 0.74 | MAOB (0.35) | NPC1RAB9AALDH1A1MAPTCA14 | |
| SCHEMBL8077684 | 0.73 | DRD2 (0.37) | NPC1RAB9ASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL9521923 | 0.73 | NOTUM (0.35) | CA14CYP11B1CYP11B2PTGS1PTGS2 | |
| SCHEMBL5657856 | 0.72 | CYP11B1 (0.44) | NPC1RAB9ASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL8074721 | 0.72 | CYP11B1 (0.34) | NPC1RAB9ASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL31593929 | 0.71 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL798296 | 0.71 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL28655422 | 0.71 | CYP11B1 (0.55) | NPC1RAB9ASMN1; SMN2KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166072-A | Amino acid derivatives | ALLELIX NEUROSCIENCE, INC. (CA) | 2000-12-26 | — | — | US | disclosed |