Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NR1I3 | Q14994 | 5/20 | 0.35 |
| ▸ | POLQ | O75417 | 2/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31092792 | 0.73 | OPRL1 (0.41) | POLQGPR119 | |
| SCHEMBL31092791 | 0.73 | OPRL1 (0.41) | POLQGPR119 | |
| SCHEMBL8073130 | 0.71 | CCKBR (0.39) | CCKBRMEN1KMT2AALDH1A1NR1I3 | |
| SCHEMBL31092804 | 0.69 | USP30 (0.39) | MEN1KMT2APOLQGPR119 | |
| SCHEMBL31098764 | 0.69 | HSP90AA1 (0.42) | MEN1KMT2APOLQGPR119 | |
| SCHEMBL31098767 | 0.69 | HSP90AA1 (0.42) | MEN1KMT2APOLQGPR119 | |
| SCHEMBL8073136 | 0.68 | CCKBR (0.65) | CCKBR | |
| SCHEMBL31174473 | 0.67 | USP30 (0.43) | MEN1KMT2AGPR119 | |
| SCHEMBL31098728 | 0.67 | GPR119 (0.39) | MEN1KMT2APOLQGPR119 | |
| SCHEMBL31098808 | 0.66 | HSD17B1 (0.43) | POLQMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057311-A | TREATING EATING DISORDERS | JAMES BLACK FOUNDATION LIMITED (GB) | 2000-05-02 | — | — | US | disclosed |
| WO-1997032860-A1 | BENZODIAZONINE DERIVATIVES BINDING TO CHOLECYSTOKININ OR GASTRIN RECEPTORS | JAMES BLACK FOUNDATION LIMITED (GB) | 1997-09-12 | — | — | WO | disclosed |