Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NR1I3 | Q14994 | 5/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8057095 | 0.73 | MAPT (0.47) | CCKBRMAPT | |
| SCHEMBL8073125 | 0.71 | CCKBR (0.38) | CCKBRMEN1KMT2AALDH1A1NR1I3 | |
| SCHEMBL13000655 | 0.67 | RAB9A (0.40) | MEN1KMT2AALDH1A1TP53HTT | |
| SCHEMBL9138625 | 0.67 | RAB9A (0.43) | MEN1KMT2AALDH1A1TP53HTT | |
| SCHEMBL9135784 | 0.66 | LMNA (0.47) | MEN1KMT2AALDH1A1TP53HTT | |
| SCHEMBL13000610 | 0.64 | RAB9A (0.47) | MEN1KMT2AALDH1A1TP53HTT | |
| SCHEMBL8073136 | 0.63 | CCKBR (0.65) | CCKBR | |
| SCHEMBL13000657 | 0.62 | RAB9A (0.43) | MEN1KMT2AALDH1A1TP53HTT | |
| SCHEMBL13000509 | 0.62 | RAB9A (0.39) | MEN1KMT2AALDH1A1TP53HTT | |
| SCHEMBL29035758 | 0.62 | POLB (0.54) | CCKBRMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057311-A | TREATING EATING DISORDERS | JAMES BLACK FOUNDATION LIMITED (GB) | 2000-05-02 | — | — | US | disclosed |
| WO-1997032860-A1 | BENZODIAZONINE DERIVATIVES BINDING TO CHOLECYSTOKININ OR GASTRIN RECEPTORS | JAMES BLACK FOUNDATION LIMITED (GB) | 1997-09-12 | — | — | WO | disclosed |