Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JUN | P05412 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3919953 | 0.78 | JUN (0.52) | JUNNFKB1KDM1AHDAC1HDAC6 | |
| SCHEMBL7968621 | 0.78 | JUN (0.52) | JUNNFKB1KDM1AHDAC1HDAC6 | |
| SCHEMBL4573115 | 0.77 | JUN (0.69) | JUNNFKB1KDM1AHDAC1HDAC6 | |
| SCHEMBL4573113 | 0.77 | JUN (0.69) | JUNNFKB1KDM1AHDAC1HDAC6 | |
| SCHEMBL27396086 | 0.76 | ALDH1A1 (0.46) | JUNNFKB1KDM1AHDAC1HDAC6 | |
| SCHEMBL1821847 | 0.75 | GLA (0.60) | HDAC1HDAC6CYP1A2MAPTHTT | |
| SCHEMBL28187249 | 0.73 | ALDH1A1 (0.56) | KDM4EMAPTALDH1A1SMN1; SMN2MEN1 | |
| Acetic Acid SCHEMBL8516899 | 0.73 | JUN (0.47) | JUNNFKB1KDM1AHDAC1HDAC6 | |
| SCHEMBL8065789 | 0.71 | HSD11B1 (0.50) | CYP1A2CYP2C19TP53MAPTPOLB | |
| SCHEMBL28037422 | 0.71 | CYP1A2 (0.50) | HDAC1HDAC6CYP1A2MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6048880-A | THERAPY FOR CYTOKINE SENSITIVE DISEASES | PFIZER PHARAMACEUTICALS INC. (JP) | 2000-04-11 | — | — | US | disclosed |