Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.52 |
| ▸ | CES1 | P23141 | 2/20 | 0.52 |
| ▸ | VNN1 | O95497 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.41 |
| ▸ | CHRNG | P07510 | 1/20 | 0.41 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | CHRND | Q07001 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10914230 | 0.87 | SMN1; SMN2 (0.44) | RAB9AHSD17B1 | |
| SCHEMBL4356098 | 0.85 | CES2 (0.43) | CES2CES1HSD17B14RAB9AHSD17B1 | |
| SCHEMBL8064210 | 0.84 | LTA4H (0.48) | CES2CES1RAB9A | |
| SCHEMBL7967901 | 0.82 | CES2 (0.73) | CES2CES1VNN1MEN1KMT2A | |
| SCHEMBL8074896 | 0.82 | CES2 (0.42) | CES2CES1RAB9AHSD17B1HSD17B2 | |
| SCHEMBL8079317 | 0.81 | CES2 (0.44) | CES2CES1RAB9A | |
| SCHEMBL13664921 | 0.80 | CES2 (0.53) | CES2CES1VNN1MEN1KMT2A | |
| SCHEMBL8079269 | 0.79 | CES2 (0.52) | CES2CES1MEN1KMT2ARAB9A | |
| SCHEMBL28548204 | 0.79 | LTA4H (0.47) | CES2CES1RAB9AHSD17B1HSD17B2 | |
| SCHEMBL8074156 | 0.78 | KMT2A (0.46) | CES2CES1MEN1KMT2ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166072-A | Amino acid derivatives | ALLELIX NEUROSCIENCE, INC. (CA) | 2000-12-26 | — | — | US | disclosed |
| WO-1999034790-A1 | GLYCINE TRANSPORT INHIBITORS | ALLELIX NEUROSCIENCE, INC. (US) | 1999-07-15 | — | — | WO | disclosed |