Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10914230 | 0.88 | SMN1; SMN2 (0.44) | LMNAALDH1A1GAAATMNPC1 | |
| SCHEMBL8074896 | 0.87 | CES2 (0.42) | LTA4HHTR7LMNAALDH1A1CES2 | |
| SCHEMBL28548204 | 0.87 | LTA4H (0.47) | LTA4HHTR7LMNAALDH1A1GAA | |
| SCHEMBL8079269 | 0.84 | CES2 (0.52) | LMNAALDH1A1CES2CES1NPC1 | |
| SCHEMBL8074703 | 0.84 | CES2 (0.52) | CES2CES1RAB9A | |
| SCHEMBL5074190 | 0.83 | L3MBTL1 (0.57) | LMNAALDH1A1ATMNPC1RAB9A | |
| SCHEMBL8079285 | 0.82 | CES2 (0.49) | GAACES2CES1RAB9ASMN1; SMN2 | |
| SCHEMBL8079262 | 0.79 | NPC1 (0.49) | LMNAALDH1A1GAANPC1RAB9A | |
| SCHEMBL8079317 | 0.79 | CES2 (0.44) | GAACES2CES1NPC1RAB9A | |
| SCHEMBL3406790 | 0.79 | LMNA (0.65) | LTA4HHTR7LMNAALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166072-A | Amino acid derivatives | ALLELIX NEUROSCIENCE, INC. (CA) | 2000-12-26 | — | — | US | disclosed |
| WO-1999034790-A1 | GLYCINE TRANSPORT INHIBITORS | ALLELIX NEUROSCIENCE, INC. (US) | 1999-07-15 | — | — | WO | disclosed |