SCHEMBL921994

SCHEMBL921994

Fc1[c]ccc(OCc2ccccc2F)c1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAOB P27338 9/20 0.50
PARP15 Q460N3 3/20 0.50
PARP10 Q53GL7 3/20 0.50
PARP14 Q460N5 1/20 0.47
TSHR P16473 2/20 0.46
KDM4E B2RXH2 1/20 0.46
LMNA P02545 1/20 0.46
HTT P42858 1/20 0.46
IDO1 P14902 2/20 0.44
PKM P14618 1/20 0.43
AR P10275 1/20 0.42
HPD P32754 1/20 0.42
PTPN1 P18031 1/20 0.42
NPC1 O15118 1/20 0.42
CASP3 P42574 1/20 0.42
RAB9A P51151 1/20 0.42
SENP8 Q96LD8 1/20 0.42
SENP7 Q9BQF6 1/20 0.42
SENP6 Q9GZR1 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL920923 0.84 NR4A2 (0.49) MAOBLMNAHTTIDO1AR
SCHEMBL921406 0.84 CDK4 (0.46) MAOBPARP15PARP10KDM4E
SCHEMBL921217 0.82 PARP10 (0.53) MAOBPARP15PARP10PARP14IDO1
SCHEMBL920795 0.81 MAOB (0.46) MAOBKDM4ENPC1RAB9A
SCHEMBL23851486 0.80 HPD (0.45) MAOBHPD
SCHEMBL920621 0.80 ALOX5 (0.51) MAOBLMNARAB9A
SCHEMBL863430 0.80 MAOB (0.60) MAOBPARP15PARP10PARP14TSHR
SCHEMBL8074756 0.77 MCL1 (0.45) KDM4ELMNAHTTIDO1PKM
SCHEMBL920241 0.75 ALDH1A1 (0.47) PARP10KDM4ELMNANPC1RAB9A
SCHEMBL17644774 0.75 MAOB (0.68) MAOBPARP15PARP10PARP14TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110201649-A1 AGRICULTURAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-18 US disclosed
EP-2345328-A1 COMPOSITION FOR AGRICULTURAL USE Sumitomo Chemical Company, Limited (JP) 2011-07-20 EP disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 MAOB 3730/4885PARP15 4078/4885PARP10 4735/4885
US-20110201649-A1 AGRICULTURAL COMPOSITION H1-0, H1-3, H1-2 MAOB 4351/4885PARP15 4508/4885PARP10 4487/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.