SCHEMBL8074869

SCHEMBL8074869

CCC(C)c1[c]c(C)ccc1

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.36
HDAC4 P56524 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
TRPA1 O75762 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL184762 0.87 TSHR (0.41) TSHRHDAC4HDAC2HDAC8TRPA1
SCHEMBL16440037 0.82 TSHR (0.35) TSHRHDAC4HDAC2HDAC8
SCHEMBL249427 0.81 TSHR (0.38) TSHRHDAC4HDAC2HDAC8
SCHEMBL466363 0.78 FAAH (0.32) TSHR
SCHEMBL16440057 0.78 TSHR (0.35) TSHRHDAC4HDAC2HDAC8
SCHEMBL2696941 0.78 TSHR (0.35) TSHRHDAC4HDAC2HDAC8
SCHEMBL2776672 0.78 TSHR (0.35) TSHRHDAC4HDAC2HDAC8
SCHEMBL11504243 0.75 TSHR (0.33) TSHRHDAC4HDAC2HDAC8
SCHEMBL11503835 0.75 TSHR (0.33) TSHRHDAC4HDAC2HDAC8
SCHEMBL11503678 0.75 GABRA1 (0.34) TSHRHDAC4HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0692517-B1 Process for the preparation of crosslinked polymer particles containing fluorescent dyes BASF AG (DE) 2000-10-18 EP disclosed
US-5736596-A Use of thermoplastic electroluminescent materials which are stable for an extended period BASF AKTIENGESELLSCHAFT (DE) 1998-04-07 US disclosed
US-5710197-A METHYL METHACRYLATE POLYMER AND FLUORESCENT PERYLENE OR COUMARIN PIGMENTS BASF AKTIENGESELLSCHAFT (DE) 1998-01-20 US disclosed
EP-0698649-A1 Use of thermoplastically processible long time stable electroluminescent materials BASF AKTIENGESELLSCHAFT (DE) 1996-02-28 EP disclosed
EP-0692517-A1 Crosslinked polymer particules containing fluorescent dyes BASF AKTIENGESELLSCHAFT (DE) 1996-01-17 EP disclosed
EP-0422474-B1 Fluorescent pigments BASF AG (DE) 1995-11-29 EP disclosed
US-5470502-A Lightfast BASF AKTIENGESELLSCHAFT (DE) 1995-11-28 US disclosed
EP-0422535-B1 Polymerisable perylene-3,4,9,10-tetracarboxylic diimides and polymeric products thereof BASF AG (DE) 1994-03-02 EP disclosed
EP-0432445-B1 FLUORESCENT PRINTING INK BASF Lacke + Farben AG (DE) 1993-06-02 EP disclosed
EP-0432445-A2 Fluorescent printing ink BASF Lacke + Farben AG (DE) 1991-06-19 EP disclosed
EP-0422474-A2 Fluorescent pigments BASF Aktiengesellschaft (DE) 1991-04-17 EP disclosed
EP-0422535-A1 Polymerisable perylene-3,4,9,10-tetracarboxylic diimides and polymeric products thereof BASF Aktiengesellschaft (DE) 1991-04-17 EP disclosed
US-4169106-A Antiarrhythmic N,N'-bis(phenylcarbamoylalkyl)amidines COOPER LABORATORIES, INC. (US) 1979-09-25 US disclosed