Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL184762 | 0.85 | TSHR (0.41) | TSHRHDAC4HDAC2HDAC8 | |
| SCHEMBL249427 | 0.79 | TSHR (0.38) | TSHRHDAC4HDAC2HDAC8 | |
| SCHEMBL2698492 | 0.79 | CYP1A2 (0.31) | TSHR | |
| SCHEMBL8074869 | 0.78 | TSHR (0.36) | TSHRHDAC4HDAC2HDAC8 | |
| SCHEMBL16440057 | 0.76 | TSHR (0.35) | TSHRHDAC4HDAC2HDAC8 | |
| SCHEMBL2776672 | 0.76 | TSHR (0.35) | TSHRHDAC4HDAC2HDAC8 | |
| SCHEMBL16440037 | 0.76 | TSHR (0.35) | TSHRHDAC4HDAC2HDAC8 | |
| SCHEMBL11504243 | 0.73 | TSHR (0.33) | TSHRHDAC4HDAC2HDAC8 | |
| SCHEMBL11503835 | 0.73 | TSHR (0.33) | TSHRHDAC4HDAC2HDAC8 | |
| SCHEMBL11503678 | 0.73 | GABRA1 (0.34) | TSHRHDAC4HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104245665-B | The manufacture method of alkylated aromatic amide derivatives | 三井化学AGRO株式会社 | 2017-08-25 | — | — | CN | disclosed |
| US-9353046-B2 | Method for producing alkylated aromatic amide derivative | MITSUI CHEMICALS AGRO, INC. (JP) | 2016-05-31 | — | — | US | disclosed |
| US-20150065721-A1 | METHOD FOR PRODUCING ALKYLATED AROMATIC AMIDE DERIVATIVE | MITSUI CHEMICALS AGRO, INC. (JP) | 2015-03-05 | — | — | US | disclosed |
| EP-2835366-A1 | METHOD FOR PRODUCING ALKYLATED AROMATIC AMIDE DERIVATIVE | Mitsui Chemicals Agro, Inc. (JP) | 2015-02-11 | — | — | EP | disclosed |
| EP-2632929-A1 | N-HETEROCYCLIC CARBENE COMPLEXES, THEIR PREPARATION AND USE | BASF SE (DE) | 2013-09-04 | — | — | EP | disclosed |
| WO-2012056419-A1 | N-HETEROCYCLIC CARBENE COMPLEXES, THEIR PREPARATION AND USE | BASF SE (DE) | 2012-05-03 | — | — | WO | disclosed |
| US-20120108819-A1 | N-Heterocyclic Carbene Complexes, Their Preparation And Use | BASF SE (DE) | 2012-05-03 | — | — | US | disclosed |
| US-4169106-A | Antiarrhythmic N,N'-bis(phenylcarbamoylalkyl)amidines | COOPER LABORATORIES, INC. (US) | 1979-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150065721-A1 | METHOD FOR PRODUCING ALKYLATED AROMATIC AMIDE DERIVATIVE | NAT1, HAX1, AOC2 | TSHR 280/4885HDAC4 558/4885HDAC2 268/4885 |
| US-20120108819-A1 | N-Heterocyclic Carbene Complexes, Their Preparation And Use | CYCS, CYC1, CBR1 | TSHR 2874/4885HDAC4 4014/4885HDAC2 1289/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.