Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | LPAR1 | Q92633 | 9/20 | 0.44 |
| ▸ | LPAR5 | Q9H1C0 | 9/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8070153 | 0.99 | PKM (0.47) | PKMPOLBTHRATHRBLPAR1 | |
| SCHEMBL8070527 | 0.90 | PKM (0.54) | PKMPOLBLPAR1LPAR5TTR | |
| SCHEMBL8068481 | 0.89 | THRA (0.43) | PKMPOLBTHRATHRBLPAR1 | |
| SCHEMBL8444218 | 0.86 | PKM (0.44) | PKMPOLBTHRATHRBLPAR1 | |
| SCHEMBL8059406 | 0.85 | SLC9A1 (0.47) | — | |
| Hydrochloric Acid SCHEMBL8073687 | 0.85 | PKM (0.43) | PKMPOLBTHRATHRBLPAR1 | |
| SCHEMBL8073825 | 0.84 | PKM (0.47) | PKMPOLBTHRATHRBTTR | |
| SCHEMBL8068578 | 0.84 | LPAR1 (0.43) | THRATHRBLPAR1LPAR5 | |
| SCHEMBL8073502 | 0.84 | TTR (0.51) | PKMPOLBTTR | |
| SCHEMBL8059397 | 0.83 | THRA (0.42) | PKMPOLBTHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057322-A | USEFUL IN TREATMENT OF CARDIOVASCULAR DISEASES | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-05-02 | — | — | US | disclosed |
| EP-0723956-B1 | Basically substituted benzoylguanidines, process for their preparation, their use as medicaments or diagnostics as well as medicaments containing them | HOECHST AG (DE) | 1999-10-13 | — | — | EP | disclosed |
| EP-0723956-A1 | Basically substituted benzoylguanidines, process for their preparation, their use as medicaments or diagnostics as well as medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-07-31 | — | — | EP | disclosed |