SCHEMBL8075701

SCHEMBL8075701

Nc1cc(C(=O)O)ccc1S(=O)(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 1/20 0.59
NEU3 Q9UQ49 1/20 0.46
KDM4E B2RXH2 9/20 0.45
GAA P10253 8/20 0.45
ALDH1A1 P00352 6/20 0.45
HPGD P15428 4/20 0.45
PKM P14618 2/20 0.45
MAPT P10636 5/20 0.45
HSD17B10 Q99714 4/20 0.45
THRB P10828 3/20 0.45
GFER P55789 2/20 0.45
HTT P42858 1/20 0.45
PLEC Q15149 1/20 0.45
LCK P06239 1/20 0.44
FYN P06241 1/20 0.44
TDP1 Q9NUW8 3/20 0.44
L3MBTL1 Q9Y468 3/20 0.44
POLB P06746 2/20 0.44
LMNA P02545 1/20 0.43
CASP1 P29466 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9659136 0.85 CDC25B (0.45) CDC25BNEU3KDM4EGAAALDH1A1
SCHEMBL29870405 0.85 CDC25B (0.59) CDC25BNEU3KDM4EGAAALDH1A1
SCHEMBL9177276 0.85 CDC25B (0.59) CDC25BNEU3KDM4EGAAALDH1A1
SCHEMBL1363387 0.85 CDC25B (0.76) CDC25BNEU3KDM4EGAAALDH1A1
SCHEMBL6764607 0.83 CDC25B (0.58) CDC25BNEU3KDM4EGAAALDH1A1
SCHEMBL11860250 0.83 CDC25B (0.73) CDC25BNEU3KDM4EGAAALDH1A1
SCHEMBL8958857 0.82 MAPK1 (0.53) KDM4EGAAALDH1A1HPGDPKM
SCHEMBL7542974 0.82 CDC25B (0.55) CDC25BNEU3KDM4EGAAPKM
SCHEMBL7824943 0.81 PKM (0.52) KDM4EGAAALDH1A1HPGDPKM
SCHEMBL9500692 0.80 CDC25B (0.54) CDC25BNEU3KDM4EGAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0582687-A4 PERMANENTLY STAIN RESISTANT TEXTILE FIBERS. PEACH STATE LABS INC (US) 1994-12-14 EP claimed
US-5316850-A Permanently stain resistant textile fibers PEACH STATE LABS, INC. (US) 1994-05-31 US claimed
EP-0582687-A1 PERMANENTLY STAIN RESISTANT TEXTILE FIBERS PEACH STATE LABS, INC. (US) 1994-02-16 EP claimed
WO-1992018332-A1 PERMANENTLY STAIN RESISTANT TEXTILE FIBERS PEACH STATE LABS, INC. (US) 1992-10-29 WO claimed
EP-0261079-B1 REACTIVE DYES, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1991-10-16 EP claimed
US-11772085-B2 Far superior oxidation catalysts based on macrocyclic compounds CARNEGIE MELLON UNIVERSITY (US) 2023-10-03 US disclosed
EP-4015511-A1 OXIDATION CATALYSTS BASED ON MACROCYCLIC COMPOUNDS CARNEGIE MELLON UNIVERSITY (US) 2022-06-22 EP disclosed
EP-0735113-B1 Mixtures of reactive dyes and their use CIBA SC HOLDING AG (CH) 2000-10-18 EP disclosed
EP-0309406-B2 Reactive dyes, their preparation and their use CIBA SC HOLDING AG (CH) 2000-07-12 EP disclosed
US-5892006-A CONTAINING S-TRIAZINE RINGS CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-04-06 US disclosed
US-5735911-A TRIAZINE DYES HAVING GOOD WET AND LIGHT FASTNESS PROPERTIES CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-04-07 US disclosed
US-5731421-A COLORFASTNESS CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-03-24 US disclosed
US-4330469-A Reactive dyes, processes for their manufacture and their use CIBA-GEIGY CORPORATION (US) 1982-05-18 US disclosed
US-4325869-A CONTAINING A PYRIMIDINE RING AND ONE OR MORE AZO GROUPS CIBA-GEIGY CORPORATION (US) 1982-04-20 US disclosed
EP-0045278-A2 Reactive dyestuffs, their preparation and their use CIBA-GEIGY AG (CH) 1982-02-03 EP disclosed
EP-0041922-A1 Process for the preparation of amino-substituted 1-amino-8-hydroxy-naphthalene-sulfonic acids CIBA-GEIGY AG (CH) 1981-12-16 EP disclosed
EP-0036838-A2 Azo dyestuffs, their preparation and their use CIBA-GEIGY AG (CH) 1981-09-30 EP disclosed
US-4283331-A FIBER-REACTIVE DYES CIBA-GEIGY CORPORATION (US) 1981-08-11 US disclosed
US-4270918-A METALLIZED TRIAZINE-FUNCTIONAL MONOAZO DYE CIBA-GEIGY CORPORATION (US) 1981-06-02 US disclosed
EP-0012289-A1 Anthraquinone reactive dyestuffs, their preparation and their use in dyeing materials that contain hydroxyl or nitrogen groups BAYER AG (DE) 1980-06-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11772085-B2 Far superior oxidation catalysts based on macrocyclic compounds SOD1, ME3, ME2 CDC25B 659/4885NEU3 916/4885KDM4E 354/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.