Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | RAD52 | P43351 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3298289 | 0.84 | KCNH3 (0.73) | KCNH3GAALMNARAD52 | |
| SCHEMBL18062211 | 0.80 | SMN1; SMN2 (0.46) | SMN1; SMN2HSD17B10GAAPPARGLMNA | |
| SCHEMBL8070572 | 0.80 | RAB9A (0.54) | SMN1; SMN2HSD17B10KCNH3GAALMNA | |
| SCHEMBL14869398 | 0.79 | BCHE (0.65) | KCNH3GAALMNARAD52 | |
| SCHEMBL13194932 | 0.79 | APP (0.68) | SMN1; SMN2KCNH3GAALMNARAD52 | |
| SCHEMBL3459285 | 0.77 | LMNA (0.56) | SMN1; SMN2HSD17B10GAALMNAHTT | |
| SCHEMBL3459282 | 0.76 | SMN1; SMN2 (0.51) | SMN1; SMN2HSD17B10GAAPPARGLMNA | |
| SCHEMBL12321866 | 0.76 | MEN1 (0.53) | SMN1; SMN2HSD17B10GAAPPARGLMNA | |
| SCHEMBL3461164 | 0.75 | HTT (0.60) | SMN1; SMN2GAALMNAHTT | |
| SCHEMBL11788237 | 0.75 | KCNH3 (0.61) | KCNH3GAALMNARAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648755-B1 | Improved process for the preparation of 2,4-di(alkylamino)-6-alkylthio-s-triazines and 2-alkylamino-4,6-di(alkylthio)-s-triazines | CIBA SC HOLDING AG (CH) | 2000-08-02 | — | — | EP | disclosed |
| US-5420274-A | Process for the preparation of 2,4-di(alkylamino)-6-alkylthio-s-triazines | CIBA-GEIGY CORPORATION (US) | 1995-05-30 | — | — | US | disclosed |
| EP-0648755-A1 | Improved process for the preparation of 2,4-Di(alkylamino)-6-alkylthio-s-triazines | CIBA-GEIGY AG (CH) | 1995-04-19 | — | — | EP | disclosed |