Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8076307 | 0.84 | KMT2A (0.47) | KMT2AMEN1BCHEALDH1A1HPGD | |
| SCHEMBL8076273 | 0.82 | KMT2A (0.67) | KMT2AMEN1TFPI2ALDH1A1SMN1; SMN2 | |
| SCHEMBL2114760 | 0.81 | L3MBTL1 (0.54) | KMT2AMEN1BCHETFPI2ALDH1A1 | |
| SCHEMBL8083508 | 0.81 | P2RX4 (0.46) | KMT2AMEN1TFPI2ALDH1A1HPGD | |
| SCHEMBL24746766 | 0.79 | L3MBTL1 (0.47) | KMT2AMEN1BCHEALDH1A1HPGD | |
| SCHEMBL1196432 | 0.78 | L3MBTL1 (0.62) | KMT2AMEN1BCHETFPI2L3MBTL1 | |
| SCHEMBL27887683 | 0.78 | TFPI2 (0.51) | KMT2AMEN1TFPI2ALDH1A1KDM4E | |
| SCHEMBL887130 | 0.76 | CREBBP (0.55) | KMT2AMEN1TFPI2ALDH1A1HPGD | |
| SCHEMBL30622597 | 0.76 | TFPI2 (0.54) | KMT2AMEN1TFPI2ALDH1A1HPGD | |
| SCHEMBL2594979 | 0.76 | TFPI2 (0.54) | KMT2AMEN1TFPI2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0555537-B1 | Endothelin antagonists | BANYU PHARMA CO LTD (JP) | 2000-11-02 | — | — | EP | disclosed |
| US-5614498-A | OLIGOPEPTIDES, BRONCHDILATORS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1997-03-25 | — | — | US | disclosed |
| US-5496928-A | Endothelin antagonistic substance | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-03-05 | — | — | US | disclosed |
| EP-0555537-A2 | Endothelin antagonistic substance | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-08-18 | — | — | EP | disclosed |