Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ELANE | P08246 | 2/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8089259 | 0.91 | L3MBTL1 (0.47) | L3MBTL1KDM4EMEN1KMT2ACREBBP | |
| SCHEMBL8083502 | 0.88 | BCHE (0.49) | L3MBTL1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL8530899 | 0.86 | KDM1A (0.48) | L3MBTL1MEN1KMT2AALDH1A1TFPI2 | |
| SCHEMBL8083508 | 0.86 | P2RX4 (0.46) | L3MBTL1KDM4EMEN1KMT2ACREBBP | |
| SCHEMBL6283431 | 0.85 | L3MBTL1 (0.53) | L3MBTL1KDM4EMEN1KMT2ACREBBP | |
| SCHEMBL8076273 | 0.85 | KMT2A (0.67) | L3MBTL1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL2544694 | 0.84 | L3MBTL1 (0.52) | L3MBTL1KDM4EMEN1KMT2ACREBBP | |
| SCHEMBL2457012 | 0.83 | KMT2A (0.64) | L3MBTL1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL15902156 | 0.83 | ALDH1A1 (0.67) | L3MBTL1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL9164757 | 0.81 | L3MBTL1 (0.60) | L3MBTL1KDM4EMEN1KMT2ACREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130123326-A1 | ALLOSTERIC BINDING COMPOUNDS | REGION MIDTJYLLAND (DK) | 2013-05-16 | — | — | US | claimed |
| US-20120095048-A1 | ALLOSTERIC BINDING COMPOUNDS | REGION MIDT JYLLAND (DK) | 2012-04-19 | — | — | US | claimed |
| EP-2398760-A1 | ALLOSTERIC BINDING COMPOUNDS | Aarhus Universitet (DK) | 2011-12-28 | — | — | EP | claimed |
| WO-2010094289-A1 | ALLOSTERIC BINDING COMPOUNDS | AARHUS UNIVERSITET (DK) | 2010-08-26 | — | — | WO | claimed |
| EP-1486207-A2 | Sulfonated amino acid derivatives and metalloproteinase inhibitors containing the same | SHIONOGI & CO., LTD. (JP) | 2004-12-15 | — | — | EP | claimed |
| US-20030225043-A1 | Sulfonated amino acid derivatives and metalloproteinase inhibitors containing the same | SHIONOGI & CO., LTD. | 2003-12-04 | — | — | US | claimed |
| US-20030139379-A1 | Sulfonated amino acid derivatives and metalloproteinase inhibitors containing the same | SHIONOGI & CO., LTD. | 2003-07-24 | — | — | US | claimed |
| EP-0950656-A1 | SULFONATED AMINO ACID DERIVATIVES AND METALLOPROTEINASE INHIBITORS CONTAINING THE SAME | SHIONOGI & CO., LTD. (JP) | 1999-10-20 | — | — | EP | claimed |
| US-20130123326-A1 | ALLOSTERIC BINDING COMPOUNDS | REGION MIDTJYLLAND (DK) | 2013-05-16 | — | — | US | disclosed |
| US-20130123326-A1 | ALLOSTERIC BINDING COMPOUNDS | REGION MIDTJYLLAND (DK) | 2013-05-16 | — | — | US | disclosed |
| US-20130123326-A1 | ALLOSTERIC BINDING COMPOUNDS | REGION MIDTJYLLAND (DK) | 2013-05-16 | — | — | US | disclosed |
| US-20120095048-A1 | ALLOSTERIC BINDING COMPOUNDS | REGION MIDT JYLLAND (DK) | 2012-04-19 | — | — | US | disclosed |
| US-20120095048-A1 | ALLOSTERIC BINDING COMPOUNDS | REGION MIDT JYLLAND (DK) | 2012-04-19 | — | — | US | disclosed |
| US-20120095048-A1 | ALLOSTERIC BINDING COMPOUNDS | REGION MIDT JYLLAND (DK) | 2012-04-19 | — | — | US | disclosed |
| US-5614498-A | OLIGOPEPTIDES, BRONCHDILATORS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1997-03-25 | — | — | US | disclosed |
| US-5496928-A | Endothelin antagonistic substance | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-03-05 | — | — | US | disclosed |
| US-5470833-A | Vasodilators, bronchodilators | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-11-28 | — | — | US | disclosed |
| US-5444152-A | Vasolidator or bronchodilator | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-08-22 | — | — | US | disclosed |
| EP-0555537-A2 | Endothelin antagonistic substance | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-08-18 | — | — | EP | disclosed |
| EP-0460679-A2 | Endothelin antagonistic peptide derivatives | Banyu Pharmaceutical Co., Ltd. (JP) | 1991-12-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030139379-A1 | Sulfonated amino acid derivatives and metalloproteinase inhibitors containing the same | MMP9, MMP2, MMP1 | L3MBTL1 4563/4885KDM4E 1991/4885MEN1 1773/4885 |
| US-20120095048-A1 | ALLOSTERIC BINDING COMPOUNDS | GRIN2C, GRM2, GRIN2B | L3MBTL1 4469/4885KDM4E 2005/4885MEN1 3403/4885 |
| US-20130123326-A1 | ALLOSTERIC BINDING COMPOUNDS | GRIN2C, GRM2, GRIN2B | L3MBTL1 4469/4885KDM4E 2005/4885MEN1 3403/4885 |
| US-20030225043-A1 | Sulfonated amino acid derivatives and metalloproteinase inhibitors containing the same | MMP9, MMP2, MMP1 | L3MBTL1 4563/4885KDM4E 1991/4885MEN1 1773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.