Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2114760 | 0.86 | L3MBTL1 (0.54) | ALDH1A1MEN1KMT2AL3MBTL1TFPI2 | |
| SCHEMBL8083506 | 0.86 | P2RX4 (0.46) | P2RX4ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL6857448 | 0.81 | KMT2A (0.71) | ALDH1A1TSHRMEN1KMT2AL3MBTL1 | |
| SCHEMBL8089259 | 0.81 | L3MBTL1 (0.47) | ALDH1A1MEN1KMT2AL3MBTL1TFPI2 | |
| SCHEMBL8076309 | 0.81 | KMT2A (0.47) | P2RX4ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL8530899 | 0.80 | KDM1A (0.48) | P2RX4ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL8083502 | 0.79 | BCHE (0.49) | ALDH1A1TSHRMEN1KMT2AL3MBTL1 | |
| SCHEMBL8076273 | 0.79 | KMT2A (0.67) | ALDH1A1MEN1KMT2AL3MBTL1TFPI2 | |
| SCHEMBL24877696 | 0.78 | HTR6 (0.52) | HDAC1HDAC8HDAC6 | |
| SCHEMBL30859499 | 0.78 | HTR6 (0.52) | HDAC1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0555537-B1 | Endothelin antagonists | BANYU PHARMA CO LTD (JP) | 2000-11-02 | — | — | EP | disclosed |
| US-5614498-A | OLIGOPEPTIDES, BRONCHDILATORS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1997-03-25 | — | — | US | disclosed |
| US-5496928-A | Endothelin antagonistic substance | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-03-05 | — | — | US | disclosed |
| EP-0555537-A2 | Endothelin antagonistic substance | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-08-18 | — | — | EP | disclosed |