Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.36 |
| ▸ | CUL4A | Q13619 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PPOX | P50336 | 1/20 | 0.32 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.32 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.32 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8088035 | 0.89 | TSHR (0.41) | TSHRTDP1L3MBTL1SCN9ACA2 | |
| SCHEMBL8604258 | 0.85 | CUL4A (0.49) | TSHRCUL4AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL8084592 | 0.83 | CUL4A (0.46) | CUL4ALMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL8370837 | 0.82 | NPC1 (0.37) | L3MBTL1CUL4AMAPTHPGDALDH1A1 | |
| SCHEMBL8603914 | 0.82 | CUL4A (0.39) | TSHRTDP1L3MBTL1CUL4ALMNA | |
| SCHEMBL8602332 | 0.82 | RORC (0.35) | SCN9ACUL4ALMNAMAPTHPGD | |
| SCHEMBL11806580 | 0.81 | TSHR (0.63) | TSHRTDP1L3MBTL1CUL4ACA2 | |
| SCHEMBL8598738 | 0.80 | ELANE (0.43) | TSHRTDP1L3MBTL1CUL4ALMNA | |
| SCHEMBL8602520 | 0.80 | CUL4A (0.33) | TSHRCUL4ALMNAMAPTHPGD | |
| SCHEMBL8084425 | 0.80 | TSHR (0.40) | TSHRTDP1L3MBTL1CUL4ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0493606-B1 | HETEROCYCLE-SUBSTITUTED BENZENE DERIVATIVE, PRODUCTION THEREOF, AND HERBICIDE CONTAINING THE SAME AS ACTIVE INGREDIENT | SAGAMI CHEM RES (JP) | 2000-10-18 | — | — | EP | disclosed |
| EP-1006105-A1 | Benzene derivatives | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2000-06-07 | — | — | EP | disclosed |
| US-5464811-A | Benzene derivatives substituted with heterocyclic ring and herbicides containing same as active ingredients | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1995-11-07 | — | — | US | disclosed |
| US-5424277-A | An N-substituted-3,4,5,6-tetrahydrophthalimide derivative characterized by having a cycloalkoxy group at the 5-position of the phenyl ring on the nitrogen | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1995-06-13 | — | — | US | disclosed |
| EP-0493606-A1 | HETEROCYCLE-SUBSTITUTED BENZENE DERIVATIVE, PRODUCTION THEREOF, AND HERBICIDE CONTAINING THE SAME AS ACTIVE INGREDIENT | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1992-07-08 | — | — | EP | disclosed |