Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CUL4A | Q13619 | 3/20 | 0.49 |
| ▸ | PPOX | P50336 | 3/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8603914 | 0.89 | CUL4A (0.39) | CUL4APPOXSMN1; SMN2HTR4CYP1A2 | |
| SCHEMBL8598738 | 0.86 | ELANE (0.43) | CUL4ASMN1; SMN2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8370837 | 0.86 | NPC1 (0.37) | CUL4AALDH1A1NPC1GAAMAPT | |
| SCHEMBL8603207 | 0.85 | ELANE (0.40) | TSHRALDH1A1NPC1KDM4EMAPT | |
| SCHEMBL8076435 | 0.85 | TSHR (0.44) | CUL4APPOXSMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL8084592 | 0.83 | CUL4A (0.46) | CUL4ARORCSMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL16068644 | 0.82 | CUL4A (0.49) | CUL4APPOXRORCSMN1; SMN2TSHR | |
| SCHEMBL8602520 | 0.81 | CUL4A (0.33) | CUL4APPOXSMN1; SMN2HTR4CYP1A2 | |
| SCHEMBL7533766 | 0.80 | PPOX (0.56) | PPOXTSHRALDH1A1GAAKDM4E | |
| SCHEMBL7722991 | 0.80 | MEN1 (0.37) | PPOXSMN1; SMN2HTR4CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6025122-A | — | — | None | — | — | JP | disclosed |
| US-9580444-B2 | Polycyclic pyrazolinone derivative and herbicide comprising same as effective component thereof | SAGAMI CHEMICAL RESEARCH INSTITUTE (JP) | 2017-02-28 | — | — | US | disclosed |
| US-20160024110-A1 | POLYCYCLIC PYRAZOLINONE DERIVATIVE AND HERBICIDE COMPRISING SAME AS EFFECTIVE COMPONENT THEREOF | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2016-01-28 | — | — | US | disclosed |
| WO-2014142307-A1 | POLYCYCLIC PYRAZOLINONE DERIVATIVE AND HERBICIDE COMPRISING SAME AS EFFECTIVE COMPONENT THEREOF | 公益財団法人相模中央化学研究所 (JP) | 2014-09-18 | — | — | WO | disclosed |
| CN-101215289-A | 3-substituted phenyl-pyrazolo[3,4-d][1,2,3]triazin-4-one compounds with PPO restraining activity and weeding activity | UNIV NANKAI (CN) | 2008-07-09 | — | — | CN | disclosed |
| EP-0626370-B1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL CO (JP) | 1998-02-11 | — | — | EP | disclosed |
| EP-0650957-A4 | ANILINE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME. | SUMITOMO CHEMICAL CO (JP) | 1995-08-09 | — | — | EP | disclosed |
| EP-0650957-A1 | ANILINE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1995-05-03 | — | — | EP | disclosed |
| EP-0626370-A1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1994-11-30 | — | — | EP | disclosed |
| WO-1994021597-A1 | ANILINE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1994-09-29 | — | — | WO | disclosed |
| JP-H0625122-A | ANILINE DERIVATIVE AND ITS PRODUCTION | SUMITOMO CHEM CO LTD | 1994-02-01 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160024110-A1 | POLYCYCLIC PYRAZOLINONE DERIVATIVE AND HERBICIDE COMPRISING SAME AS EFFECTIVE COMPONENT THEREOF | DDT, PDHX, CYP4X1 | CUL4A 247/4885PPOX 432/4885RORC 2279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.