Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.41 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14801551 | 0.78 | TSHR (0.46) | TSHRGABRR1GABRR2BLMGABRR3 | |
| SCHEMBL455399 | 0.78 | TSHR (0.46) | TSHRGABRR1GABRR2BLMGABRR3 | |
| SCHEMBL3084515 | 0.78 | TSHR (0.46) | TSHRGABRR1GABRR2BLMGABRR3 | |
| SCHEMBL3084517 | 0.78 | TSHR (0.46) | TSHRGABRR1GABRR2BLMGABRR3 | |
| SCHEMBL1538365 | 0.74 | TSHR (0.42) | TSHRGABRR1GABRR2BLMGABRR3 | |
| SCHEMBL20625018 | 0.74 | TSHR (0.42) | TSHRGABRR1GABRR2BLMGABRR3 | |
| SCHEMBL712787 | 0.74 | TSHR (0.42) | TSHRGABRR1GABRR2BLMGABRR3 | |
| SCHEMBL24950 | 0.69 | — | — | |
| SCHEMBL24951 | 0.69 | — | — | |
| SCHEMBL2467205 | 0.69 | TSHR (0.46) | TSHRGABRR1GABRR2BLMGABRR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1028938-A1 | PRODUCTION OF AMINOHALOGENCROTONATES | Solvay Fluor und Derivate GmbH (DE) | 2000-08-23 | — | — | EP | disclosed |
| WO-1999024390-A1 | PRODUCTION OF AMINOHALOGENCROTONATES | SOLVAY FLUOR UND DERIVATE GMBH (DE) | 1999-05-20 | — | — | WO | disclosed |