Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 9/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.59 |
| ▸ | CA1 | P00915 | 12/20 | 0.54 |
| ▸ | CA2 | P00918 | 12/20 | 0.54 |
| ▸ | CA12 | O43570 | 11/20 | 0.54 |
| ▸ | CA9 | Q16790 | 11/20 | 0.54 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5672972 | 0.86 | CA12 (0.60) | PTGS2PTGS1CA1CA2CA12 | |
| SCHEMBL8070312 | 0.83 | PTGS2 (0.47) | PTGS2PTGS1CA1CA2CA12 | |
| SCHEMBL5674068 | 0.81 | CA12 (0.62) | PTGS2PTGS1CA1CA2CA12 | |
| SCHEMBL8407587 | 0.80 | CA2 (0.42) | PTGS2PTGS1CA1CA2CA12 | |
| SCHEMBL5671527 | 0.79 | PTGS2 (0.56) | PTGS2PTGS1CA1CA2CA12 | |
| SCHEMBL5672477 | 0.79 | CA12 (0.48) | PTGS2PTGS1CA1CA2CA12 | |
| SCHEMBL5671515 | 0.74 | CA2 (0.57) | PTGS2CA1CA2CA12CA9 | |
| SCHEMBL8061294 | 0.74 | PTGS2 (0.52) | PTGS2PTGS1CA1CA2CA12 | |
| SCHEMBL8724654 | 0.74 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL8071992 | 0.71 | PTGS2 (0.51) | PTGS2PTGS1CA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023277-A1 | NOVEL 3,4-DIARYLTHIAZOLIN-2-ONE OR -2-THIONE DERIVATIVES, PREPARATION METHODS AND USES IN THERAPY | LABORATOIRES UPSA (FR) | 2000-08-02 | — | — | EP | disclosed |
| WO-1999018093-A1 | NOVEL 3,4-DIARYLTHIAZOLIN-2-ONE OR -2-THIONE DERIVATIVES, PREPARATION METHODS AND USES IN THERAPY | LABORATOIRES UPSA (FR) | 1999-04-15 | — | — | WO | disclosed |