Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.42 |
| ▸ | CA12 | O43570 | 4/20 | 0.42 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | CA9 | Q16790 | 4/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.42 |
| ▸ | F10 | P00742 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6739469 | 0.71 | PTGS2 (0.39) | CA2CA12CA1CA9PTGS2 | |
| SCHEMBL22587920 | 0.69 | PTGES2 (0.50) | CA2CA1PTGS2F10PTGS1 | |
| SCHEMBL29588398 | 0.69 | PTGES2 (0.50) | CA2CA1PTGS2F10PTGS1 | |
| SCHEMBL8407589 | 0.68 | PGR (0.47) | CYP1A2CYP2C19 | |
| SCHEMBL8404842 | 0.67 | CA2 (0.42) | CA2CA12CA1CA9PTGS2 | |
| SCHEMBL6725791 | 0.67 | PTGS2 (0.44) | CA2CA12CA1CA9PTGS2 | |
| SCHEMBL8660030 | 0.67 | PTGES2 (0.48) | CA2CA1PTGS2F10PTGS1 | |
| SCHEMBL5672972 | 0.65 | CA12 (0.60) | CA2CA12CA1CA9PTGS2 | |
| SCHEMBL5674068 | 0.64 | CA12 (0.62) | CA2CA12CA1CA9PTGS2 | |
| SCHEMBL8505681 | 0.64 | PTGER1 (0.45) | PTGS2F10PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859036-A | ANTIINFLAMMATORY AGENTS, ANALGESICS | LABORATORIES UPSA (FR) | 1999-01-12 | — | — | US | disclosed |