SCHEMBL8077332

SCHEMBL8077332

C=CS(=O)(=O)c1ccc([NH])c(S(=O)(=O)O)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.43
HSD17B10 Q99714 4/20 0.43
LMNA P02545 2/20 0.43
TSHR P16473 2/20 0.43
NPC1 O15118 1/20 0.43
TP53 P04637 1/20 0.43
MAPT P10636 1/20 0.43
XBP1 P17861 1/20 0.43
MAPK1 P28482 1/20 0.43
HTT P42858 1/20 0.43
RAB9A P51151 1/20 0.43
MDM2 Q00987 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
PRMT1 Q99873 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
POLB P06746 1/20 0.33
EPAS1 Q99814 1/20 0.33
KDM4E B2RXH2 1/20 0.32
HPGD P15428 1/20 0.32
NT5E P21589 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9336195 0.86 ALDH1A1 (0.43) ALDH1A1HSD17B10LMNATSHRNPC1
SCHEMBL342050 0.83 ALDH1A1 (0.44) ALDH1A1HSD17B10LMNATSHRSMN1; SMN2
SCHEMBL6561254 0.79 ALDH1A1 (0.43) ALDH1A1HSD17B10LMNATSHRNPC1
SCHEMBL12052725 0.79 LMNA (0.43) ALDH1A1HSD17B10LMNATSHRNPC1
SCHEMBL343564 0.78 SMN1; SMN2 (0.46) ALDH1A1LMNANPC1RAB9ASMN1; SMN2
SCHEMBL10346921 0.76 EPAS1 (0.45) ALDH1A1HSD17B10LMNATSHRNPC1
SCHEMBL9336200 0.75 ALDH1A1 (0.46) ALDH1A1HSD17B10LMNATSHRNPC1
SCHEMBL13391997 0.75 ALDH1A1 (0.43) ALDH1A1HSD17B10LMNATSHRNPC1
SCHEMBL13904612 0.75 TIMP3 (0.40) ALDH1A1HSD17B10LMNATSHRNPC1
SCHEMBL10346922 0.74 TDP1 (0.31) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0703906-B1 FIBER REACTIVE ANTHRAQUINONE DYES DYSTAR L P (US) 2000-08-30 EP disclosed
EP-0538785-B1 Water-soluble fiber-reactive dyes, process for their preparation and their use HOECHST AG (DE) 1997-04-09 EP disclosed
US-5539109-A Fiber-reactive triphenodioxazine dyes HOECHST CELANESE CORPORATION (US) 1996-07-23 US disclosed
US-5393884-A Water soluble blue dyes HOECHST CELANESE CORPORATION (US) 1995-02-28 US disclosed
WO-1994029282-A1 FIBER REACTIVE ANTHRAQUINONE DYES HOECHST CELANESE CORPORATION (US) 1994-12-22 WO disclosed
WO-1994021646-A1 FIBER-REACTIVE TRIPHENODIOXAZINE DYES HOECHST CELANESE CORPORATION (US) 1994-09-29 WO disclosed
US-5321134-A Water-soluble phthalocyanine dyes, processes for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1994-06-14 US disclosed
US-5302708-A Colorfastness HOECHST AKTIENGESELLSCHAFT (DE) 1994-04-12 US disclosed
US-5280110-A Fiber-reactive dye HOECHST AKTIENGESELLSCHAFT (DE) 1994-01-18 US disclosed
EP-0471702-B1 WATER-SOLUBLE REACTIVE DYES FOR FIBRES, THEIR PREPARATION AND USE HOECHST AG (DE) 1993-12-29 EP disclosed
US-5256776-A Brilliant green dyeings; fiber reactive HOECHST AKTIENGESELLSCHAFT (DE) 1993-10-26 US disclosed
US-5231172-A Water solubility HOECHST AKTIENGESELLSCHAFT (DE) 1993-07-27 US disclosed
US-5227475-A WATER-SOLUBLE FIBER-REACTIVE DYESTUFFS CONTAINING A CYANAMIDO-SUBSTITUTED TRIAZINYLAMINO-GROUPING, AND A PROCESS FOR DYEING WITH THE USE OF THESE DYES HOECHST AKTIENGESELLSCHAFT (DE) 1993-07-13 US disclosed
EP-0548792-A2 Water-soluble reactive dyes, their manufacture and their use HOECHST AKTIENGESELLSCHAFT (DE) 1993-06-30 EP disclosed
EP-0541057-A1 Water-soluble phthalocyanine dyes, process for their preparation and the use thereof HOECHST AKTIENGESELLSCHAFT (DE) 1993-05-12 EP disclosed
EP-0538785-A2 Water-soluble fiber-reactive dyes, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1993-04-28 EP disclosed
EP-0530660-A2 Water-soluble phthalocyanine dyes, process for their preparation and the use thereof HOECHST AKTIENGESELLSCHAFT (DE) 1993-03-10 EP disclosed
EP-0527441-A2 Water-soluble phthalocyanine dyes, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1993-02-17 EP disclosed