Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.37 |
| ▸ | DRD3 | P35462 | 4/20 | 0.37 |
| ▸ | PNMT | P11086 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | PGR | P06401 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9739115 | 0.77 | MMP3 (0.42) | ALDH1A1CYP11B2CYP11B1PGRMAOA | |
| SCHEMBL3363261 | 0.74 | PNMT (0.60) | DRD2DRD3PNMTCYP11B2CYP11B1 | |
| SCHEMBL29741121 | 0.74 | PNMT (0.60) | DRD2DRD3PNMTCYP11B2CYP11B1 | |
| SCHEMBL11007233 | 0.74 | CLK4 (0.49) | PGRMAOB | |
| SCHEMBL8077911 | 0.73 | NPC1 (0.36) | SMN1; SMN2ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL2794744 | 0.73 | HTR2A (0.37) | PNMTSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL17350029 | 0.73 | PNMT (0.58) | DRD2DRD3PNMTCYP11B2CYP11B1 | |
| Hydrochloric Acid SCHEMBL15205820 | 0.73 | PNMT (0.58) | DRD2DRD3PNMTCYP11B2CYP11B1 | |
| SCHEMBL7194431 | 0.72 | ALDH1A1 (0.47) | ALDH1A1TP53CYP11B2CYP11B1MAOA | |
| SCHEMBL1978737 | 0.72 | APP (0.41) | ALDH1A1NPC1RAB9ATP53HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166072-A | Amino acid derivatives | ALLELIX NEUROSCIENCE, INC. (CA) | 2000-12-26 | — | — | US | disclosed |