Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 5/20 | 0.49 |
| ▸ | PRKCB | P05771 | 4/20 | 0.49 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.49 |
| ▸ | PIM1 | P11309 | 2/20 | 0.49 |
| ▸ | PRKCH | P24723 | 1/20 | 0.49 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.49 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.49 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.45 |
| ▸ | CDK4 | P11802 | 1/20 | 0.45 |
| ▸ | CCND1 | P24385 | 1/20 | 0.45 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | PRKACA | P17612 | 1/20 | 0.44 |
| ▸ | PRKACG | P22612 | 1/20 | 0.44 |
| ▸ | PRKACB | P22694 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8080139 | 0.94 | PRKCA (0.53) | PRKCAPRKCBPRKCDPIM1PRKCH | |
| SCHEMBL8078243 | 0.81 | CCNT1 (0.38) | PRKCAPRKCBPRKCDPRKCHPRKCE | |
| SCHEMBL8075976 | 0.79 | PIM1 (0.60) | PRKCAPRKCBPRKCDPIM1PRKCH | |
| Hydrochloric Acid SCHEMBL8079978 | 0.78 | PIM1 (0.59) | PRKCAPRKCBPRKCDPIM1PRKCH | |
| SCHEMBL8075459 | 0.77 | PIM1 (0.70) | PRKCAPRKCBPRKCDPIM1PRKCH | |
| SCHEMBL8065185 | 0.76 | PRKCA (0.68) | PRKCAPRKCBPRKCDPIM1PRKCH | |
| Hydrochloric Acid SCHEMBL8064918 | 0.75 | PRKCA (0.67) | PRKCAPRKCBPRKCDPIM1PRKCH | |
| SCHEMBL8075731 | 0.75 | PIM1 (0.70) | PRKCAPIM1CAMK2DCCNE2CDK4 | |
| Hydrochloric Acid SCHEMBL8075396 | 0.74 | PRKCA (0.59) | PRKCAPRKCBPRKCDPIM1PRKCH | |
| Hydrochloric Acid SCHEMBL8074734 | 0.73 | PRKCB (0.61) | PRKCAPRKCBPRKCDPIM1PRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153641-A | Pharmaceutically active compounds | ASTRA AKTIEBOLAG (SE) | 2000-11-28 | — | — | US | disclosed |