Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 2/20 | 0.38 |
| ▸ | CDK9 | P50750 | 2/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | FLT4 | P35916 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.35 |
| ▸ | TEK | Q02763 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 2/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PRKCB | P05771 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8078425 | 0.81 | PRKCA (0.49) | GSK3BCDK2PRKCBPRKCAPRKCH | |
| SCHEMBL8073012 | 0.79 | SIRT2 (0.47) | CCNT1CDK9SIRT2GSK3AGSK3B | |
| SCHEMBL8080139 | 0.78 | PRKCA (0.53) | GSK3BCDK2PRKCBPRKCAPRKCH | |
| SCHEMBL8161873 | 0.73 | CCNT1 (0.52) | CCNT1CDK9GSK3AGSK3BCDK2 | |
| SCHEMBL8162860 | 0.71 | CCNT1 (0.53) | CCNT1CDK9SIRT2GSK3AGSK3B | |
| SCHEMBL8078434 | 0.71 | CYP3A4 (0.37) | MAPT | |
| SCHEMBL28764044 | 0.70 | NPC1 (0.46) | EGFRIGF1RSRCFLT4KDR | |
| SCHEMBL30834692 | 0.65 | CCNT1 (0.56) | CCNT1CDK9SIRT2GSK3AGSK3B | |
| SCHEMBL3155154 | 0.65 | CCNT1 (0.58) | CCNT1CDK9CDK2CCNA2PRKCA | |
| SCHEMBL8075637 | 0.65 | CCNT1 (0.50) | CCNT1CDK9SIRT2GSK3BCDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153641-A | Pharmaceutically active compounds | ASTRA AKTIEBOLAG (SE) | 2000-11-28 | — | — | US | disclosed |