Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | METAP1 | P53582 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | TOP1 | P11387 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2503627 | 0.88 | MAPT (0.47) | KMT2AMAPTSMN1; SMN2SLC6A3NPSR1 | |
| SCHEMBL28396369 | 0.85 | GABRA1 (0.46) | KMT2AHSD17B10TSHRL3MBTL1GABRA1 | |
| SCHEMBL29416762 | 0.83 | GABRA1 (0.47) | HSD17B10TSHRL3MBTL1GABRA1GABRB2 | |
| SCHEMBL19181573 | 0.83 | GABRA1 (0.47) | HSD17B10TSHRL3MBTL1GABRA1GABRB2 | |
| SCHEMBL29412194 | 0.83 | KMT2A (0.59) | KMT2AMAPTSMN1; SMN2SLC6A3NPSR1 | |
| SCHEMBL434556 | 0.83 | KMT2A (0.59) | KMT2AMAPTSMN1; SMN2SLC6A3NPSR1 | |
| SCHEMBL2513082 | 0.82 | LMNA (0.46) | KMT2AMAPTSMN1; SMN2SLC6A3GAA | |
| SCHEMBL18489472 | 0.82 | KMT2A (0.49) | KMT2AMAPTSMN1; SMN2SLC6A3NPSR1 | |
| SCHEMBL9340109 | 0.81 | KMT2A (0.58) | KMT2AMAPTSMN1; SMN2SLC6A3NPSR1 | |
| SCHEMBL159832 | 0.81 | PTGS2 (0.49) | KMT2AESR1MEN1HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6083987-A | 4-AMINO DERIVATIVE SUBSTITUTED PHENYLDIALKYLAMINE, USEFUL AS LIPID PEROXIDATION INHIBITOR | SHISEIDO CO., LTD. (JP) | 2000-07-04 | — | — | US | disclosed |