SCHEMBL19181573

SCHEMBL19181573

CC(C)Cc1ccccc1OC(=O)Oc1ccccc1CC(C)C

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.47
GABRB2 P47870 1/20 0.47
HPGD P15428 2/20 0.43
KDM4E B2RXH2 2/20 0.43
HSD17B10 Q99714 2/20 0.43
HTT P42858 2/20 0.43
MTNR1A P48039 1/20 0.39
MTNR1B P49286 1/20 0.39
POLB P06746 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
ALOX5AP P20292 1/20 0.39
ALDH1A1 P00352 2/20 0.38
TSHR P16473 2/20 0.38
THRA P10827 1/20 0.38
THRB P10828 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29416762 1.00 GABRA1 (0.47) GABRA1GABRB2HPGDKDM4EHSD17B10
SCHEMBL248141 0.92 POLB (0.43) GABRA1GABRB2HPGDKDM4EHSD17B10
SCHEMBL159832 0.87 PTGS2 (0.49) GABRA1GABRB2HPGDKDM4EHSD17B10
SCHEMBL28396369 0.87 GABRA1 (0.46) GABRA1GABRB2HPGDKDM4EHSD17B10
SCHEMBL6273089 0.87 ITGA4 (0.41) GABRA1GABRB2HPGDKDM4EHSD17B10
SCHEMBL1156947 0.86 CTSS (0.43) GABRA1GABRB2HPGDKDM4EHSD17B10
SCHEMBL1790082 0.86 ALOX15 (0.47) GABRA1GABRB2HPGDKDM4EHSD17B10
SCHEMBL248039 0.84 GABRA1 (0.47) GABRA1GABRB2HPGDKDM4EHSD17B10
SCHEMBL15899562 0.84 HPGD (0.44) HPGDKDM4EHSD17B10HTTMTNR1A
SCHEMBL15899290 0.84 TSHR (0.39) HPGDKDM4EHSD17B10HTTMTNR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220064372-A1 POLYCARBONATE POLYOL AND USES OF THE SAME DAIREN CHEMICAL CORPORATION (TW) 2022-03-03 US disclosed
US-10323145-B2 Copolycarbonate compositions with cyclic and linear oligomers and improved optical properties COVESTRO DEUTSCHLAND AG (DE) 2019-06-18 US disclosed
US-20190143582-A1 COPOLYCARBONATE AS A SUPPORTING MATERIAL IN 3-D PRINTING COVESTRO DEUTSCHLAND AG (DE) 2019-05-16 US disclosed
US-20180179378-A1 Copolycarbonate Compositions with Cyclic and Linear Oligomers and Improved Optical Properties COVESTRO DEUTSCHLAND AG (DE) 2018-06-28 US disclosed
US-9969879-B2 Copolycarbonate compositions with branch structures and linear oligomers and improved rheological properties COVESTRO DEUTSCHLAND AG (DE) 2018-05-15 US disclosed
US-20170362431-A1 COPOLYCARBONATE COMPOSITIONS WITH IMPROVED RHEOLOGICAL AND OPTICAL PROPERTIES CONTAINING DIGLYCEROLESTERS COVESTRO DEUTSCHLAND AG (DE) 2017-12-21 US disclosed
US-20170355817-A1 COPOLYCARBONATE COMPOSITIONS WITH IMPROVED PROCESSING BEHAVIOUR CONTAINING PE-WAX COVESTRO DEUTSCHLAND AG (DE) 2017-12-14 US disclosed
US-20170233571-A1 Copolycarbonate Compositions with Branch Structures and Cyclic Oligomers and Improved Rheological Properties COVESTRO DEUTSCHLAND AG (DE) 2017-08-17 US disclosed
US-20170226340-A1 Copolycarbonate Compositions with Branch Structures and Linear Oligomers and Improved Rheological Properties COVESTRO DEUTSCHLAND AG (DE) 2017-08-10 US disclosed
US-20170218197-A1 COPOLYCARBONATE COMPOSITIONS WITH CYCLIC AND LINEAR OLIGOMERS AND IMPROVED RHEOLOGICAL PROPERTIES COVESTRO DEUTSCHLAND AG (DE) 2017-08-03 US disclosed