Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.56 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.56 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.54 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.54 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.52 |
| ▸ | ACLY | P53396 | 4/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.50 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.48 |
| ▸ | KIT | P10721 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30196133 | 0.81 | KDM4E (0.70) | MKNK1MKNK2CYP11B2CYP19A1CYP11B1 | |
| SCHEMBL11342031 | 0.81 | KDM4E (0.70) | MKNK1MKNK2CYP11B2CYP19A1CYP11B1 | |
| SCHEMBL4459254 | 0.81 | KDM4E (0.59) | ACLYKDM4EMAPT | |
| SCHEMBL8083623 | 0.80 | MKNK1 (0.52) | MKNK1MKNK2CYP11B2CYP19A1CYP11B1 | |
| SCHEMBL10208603 | 0.80 | MKNK1 (0.59) | MKNK1MKNK2CYP11B2CYP19A1CYP11B1 | |
| Hydrochloric Acid SCHEMBL11336399 | 0.80 | KDM4E (0.68) | MKNK1MKNK2CYP11B2CYP19A1CYP11B1 | |
| Hydrochloric Acid SCHEMBL6130391 | 0.80 | KDM4E (0.57) | ACLYKDM4EMAPT | |
| SCHEMBL1911847 | 0.78 | NPC1 (0.65) | MKNK1MKNK2CYP11B2CYP19A1CYP11B1 | |
| SCHEMBL519862 | 0.77 | HSD17B10 (0.65) | MKNK1MKNK2CYP11B2CYP19A1CYP11B1 | |
| SCHEMBL4454661 | 0.77 | CYP11B2 (0.66) | MKNK1MKNK2CYP11B2CYP19A1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0836596-B1 | HYDRAZINE DERIVATIVES | UNIROYAL CHEM CO INC (US) | 2000-08-23 | — | — | EP | disclosed |