Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfanilamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 17/20 | 0.59 |
| ▸ | CA9 | Q16790 | 15/20 | 0.59 |
| ▸ | CA1 | P00915 | 14/20 | 0.59 |
| ▸ | CA12 | O43570 | 11/20 | 0.59 |
| ▸ | CA7 | P43166 | 8/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.59 |
| ▸ | CA4 | P22748 | 3/20 | 0.59 |
| ▸ | CA5A | P35218 | 3/20 | 0.59 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.59 |
| ▸ | CA6 | P23280 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfanilamide SCHEMBL570163 | 0.82 | CA2 (0.68) | CA2CA9CA1CA12CA7 | |
| Sulfanilamide SCHEMBL28202236 | 0.80 | CA2 (0.65) | CA2CA9CA1CA12CA7 | |
| Sulfanilamide SCHEMBL2215151 | 0.79 | CA2 (0.77) | CA2CA9CA1CA12CA7 | |
| Sulfanilamide SCHEMBL10652193 | 0.78 | CA2 (0.68) | CA2CA9CA1CA12CA7 | |
| Sulfanilamide SCHEMBL419065 | 0.77 | CA2 (0.74) | CA2CA9CA1CA12CA7 | |
| Sulfanilamide SCHEMBL28552204 | 0.77 | CA2 (0.61) | CA2CA9CA1CA12CA7 | |
| Sulfanilamide SCHEMBL8197658 | 0.77 | CA2 (0.81) | CA2CA9CA1CA12CA7 | |
| Sulfanilamide SCHEMBL4188099 | 0.77 | CA2 (0.90) | CA2CA9CA1CA12CA7 | |
| Sulfanilamide SCHEMBL740 | 0.77 | CA2 (1.00) | CA2CA9CA1CA12CA7 | |
| Sulfanilamide SCHEMBL31544839 | 0.77 | CA2 (1.00) | CA2CA9CA1CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757061-B1 | Sulfonamido substituted acetal polymers and use thereof in photosensitive compositions and lithographic printing plates | KODAK POLYCHROME GRAPHICS LLC (US) | 2000-09-13 | — | — | EP | disclosed |
| US-5849842-A | Sulfonamido substituted acetal polymers | KODAK POLYCHROME GRAPHICS, LLC (US) | 1998-12-15 | — | — | US | disclosed |
| US-5698360-A | Sulfonamido substituted acetal polymers and use thereof in photo-sensitive compositions and lithographic printing plates | SUN CHEMICAL CORPORATION (US) | 1997-12-16 | — | — | US | disclosed |
| EP-0757061-A2 | Sulfonamido substituted acetal polymers and use thereof in photosensitive compositions and lithographic printing plates | SUN CHEMICAL CORPORATION (US) | 1997-02-05 | — | — | EP | disclosed |