Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.49 |
| ▸ | CES1 | P23141 | 2/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8077694 | 0.85 | MAPT (0.41) | MAOBRAB9A | |
| SCHEMBL8079262 | 0.85 | NPC1 (0.49) | MAPK14GAAPKMRAB9AL3MBTL1 | |
| SCHEMBL8074156 | 0.83 | KMT2A (0.46) | CES2CES1MAPK14KMT2AGAA | |
| SCHEMBL8074168 | 0.83 | GAA (0.59) | CES2CES1MAPK14KMT2AGAA | |
| SCHEMBL8075163 | 0.82 | KDM4E (0.52) | CES2GAAHTTKDM4ESMN1; SMN2 | |
| SCHEMBL8074821 | 0.82 | CPS1 (0.49) | KMT2AGAAHTTRAB9A | |
| SCHEMBL8064210 | 0.82 | LTA4H (0.48) | CES2CES1GAAHTTKDM4E | |
| SCHEMBL29880739 | 0.79 | CES2 (0.63) | CES2CES1MAPK14KMT2AHTT | |
| SCHEMBL8609990 | 0.79 | CES2 (0.63) | CES2CES1MAPK14KMT2AHTT | |
| SCHEMBL15197225 | 0.78 | ALDH1A1 (0.53) | CES2CES1MAPK14KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166072-A | Amino acid derivatives | ALLELIX NEUROSCIENCE, INC. (CA) | 2000-12-26 | — | — | US | disclosed |
| WO-1999034790-A1 | GLYCINE TRANSPORT INHIBITORS | ALLELIX NEUROSCIENCE, INC. (US) | 1999-07-15 | — | — | WO | disclosed |