Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 6/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 4/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | LIPE | Q05469 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10798688 | 0.88 | PTGER1 (0.42) | MAPTMAPK1TDP1L3MBTL1PTGER1 | |
| SCHEMBL1190605 | 0.86 | MAPT (0.52) | MAPTMAPK1TDP1L3MBTL1BRD4 | |
| SCHEMBL7466776 | 0.83 | GSTP1 (0.42) | MAPTMAPK1TDP1L3MBTL1PTGER1 | |
| SCHEMBL8079401 | 0.83 | PTGER1 (0.49) | MAPTMAPK1TDP1L3MBTL1PTGER1 | |
| SCHEMBL26013299 | 0.82 | MAPT (0.63) | MAPTMAPK1TDP1L3MBTL1PTGER1 | |
| SCHEMBL3731514 | 0.79 | BRD4 (0.48) | MAPTMAPK1TDP1L3MBTL1PTGER1 | |
| SCHEMBL1119402 | 0.79 | MAPT (0.51) | MAPTMAPK1TDP1L3MBTL1BRD4 | |
| SCHEMBL3767201 | 0.79 | HTR1A (0.49) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL27880493 | 0.77 | LTA4H (0.39) | L3MBTL1BRD4LTA4HMAPK14SGMS2 | |
| SCHEMBL7455789 | 0.77 | RXRA (0.43) | MAPTL3MBTL1PTGER1RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998043649-A2 | AGE PRODUCTION INHIBITORY COMPOSITION COMPRISING A MAILLARD REACTION INHIBITOR AND VITAMIN B¿6? | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-08 | — | — | WO | disclosed |