Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 3/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.49 |
| ▸ | MME | P08473 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.49 |
| ▸ | CPA1 | P15085 | 1/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.49 |
| ▸ | YAP1 | P46937 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 3/20 | 0.46 |
| ▸ | GPR34 | Q9UPC5 | 4/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.44 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.44 |
| ▸ | ITGAV | P06756 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8672352 | 0.91 | NAALAD2 (0.53) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL8672347 | 0.91 | NAALAD2 (0.53) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL8672221 | 0.90 | NAALAD2 (0.52) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL8672575 | 0.87 | NAALAD2 (0.53) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL8672571 | 0.87 | NAALAD2 (0.53) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL8667278 | 0.84 | CCKBR (0.48) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL10723108 | 0.83 | LMNA (0.50) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL8674150 | 0.83 | MME (0.52) | MMEACE | |
| SCHEMBL6680542 | 0.83 | MME (0.52) | MMEACE | |
| SCHEMBL8674151 | 0.83 | MME (0.52) | MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882066-B1 | PEPTIDE DERIVATIVES | ZENECA LTD (GB) | 2000-09-06 | — | — | EP | claimed |