Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAALAD2 | Q9Y3Q0 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.49 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.44 |
| ▸ | GNPAT | O15228 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8672571 | 1.00 | NAALAD2 (0.53) | NAALAD2POLBHDAC3HDAC11HDAC6 | |
| SCHEMBL8672221 | 0.97 | NAALAD2 (0.52) | NAALAD2POLBHDAC3HDAC11HDAC6 | |
| SCHEMBL8672352 | 0.96 | NAALAD2 (0.53) | NAALAD2POLBHDAC3HDAC11HDAC6 | |
| SCHEMBL8672347 | 0.96 | NAALAD2 (0.53) | NAALAD2POLBHDAC3HDAC11HDAC6 | |
| SCHEMBL10723108 | 0.92 | LMNA (0.50) | POLBHDAC3HDAC11HDAC6HDAC1 | |
| SCHEMBL8667278 | 0.90 | CCKBR (0.48) | POLBHDAC3HDAC11HDAC6HDAC1 | |
| SCHEMBL30844021 | 0.88 | HDAC3 (0.47) | NAALAD2POLBHDAC3HDAC11HDAC6 | |
| SCHEMBL8079416 | 0.87 | HDAC3 (0.49) | NAALAD2HDAC3HDAC11HDAC6HDAC1 | |
| SCHEMBL31751930 | 0.87 | HDAC3 (0.49) | HDAC3HDAC11HDAC6HDAC1HDAC2 | |
| SCHEMBL15067536 | 0.87 | LMNA (0.54) | POLBHDAC3HDAC11HDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0883629-A1 | OLIGOPEPTIDES FOR DRUG DELIVERY | Emisphere Technologies, Inc. (US) | 1998-12-16 | — | — | EP | disclosed |
| WO-1997031938-A9 | OLIGOPEPTIDES FOR DRUG DELIVERY | — | 1997-11-20 | — | — | WO | disclosed |
| WO-1997031938-A1 | OLIGOPEPTIDES FOR DRUG DELIVERY | EMISPHERE TECHNOLOGIES, INC. (US) | 1997-09-04 | — | — | WO | disclosed |