Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAALAD2 | Q9Y3Q0 | 3/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.51 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 2/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | CPA1 | P15085 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8672347 | 1.00 | NAALAD2 (0.53) | NAALAD2HDAC3HDAC11HDAC6HDAC1 | |
| SCHEMBL8672221 | 0.99 | NAALAD2 (0.52) | NAALAD2HDAC3HDAC11HDAC6HDAC1 | |
| SCHEMBL8672571 | 0.96 | NAALAD2 (0.53) | NAALAD2HDAC3HDAC11HDAC6HDAC1 | |
| SCHEMBL8672575 | 0.96 | NAALAD2 (0.53) | NAALAD2HDAC3HDAC11HDAC6HDAC1 | |
| SCHEMBL8667278 | 0.92 | CCKBR (0.48) | HDAC3HDAC11HDAC6HDAC1HDAC2 | |
| SCHEMBL10723108 | 0.92 | LMNA (0.50) | HDAC3HDAC11HDAC6HDAC1HDAC2 | |
| SCHEMBL8079416 | 0.91 | HDAC3 (0.49) | NAALAD2HDAC3HDAC11HDAC6HDAC1 | |
| SCHEMBL2791669 | 0.89 | LMNA (0.54) | HDAC3HDAC11HDAC6HDAC1HDAC2 | |
| SCHEMBL15067536 | 0.89 | LMNA (0.54) | HDAC3HDAC11HDAC6HDAC1HDAC2 | |
| SCHEMBL10335229 | 0.89 | LMNA (0.54) | HDAC3HDAC11HDAC6HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0883629-A1 | OLIGOPEPTIDES FOR DRUG DELIVERY | Emisphere Technologies, Inc. (US) | 1998-12-16 | — | — | EP | disclosed |
| WO-1997031938-A1 | OLIGOPEPTIDES FOR DRUG DELIVERY | EMISPHERE TECHNOLOGIES, INC. (US) | 1997-09-04 | — | — | WO | disclosed |