Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29686939 | 0.67 | RAB9A (0.51) | HCRTR1HCRTR2 | |
| SCHEMBL4263055 | 0.67 | RAB9A (0.51) | HCRTR1HCRTR2 | |
| SCHEMBL456915 | 0.64 | NAPRT (0.50) | NPSR1KMT2AMEN1LMNAMAPT | |
| SCHEMBL30919007 | 0.64 | NAPRT (0.50) | NPSR1KMT2AMEN1LMNAMAPT | |
| SCHEMBL28314178 | 0.62 | HCRTR2 (0.49) | LMNAHCRTR1HCRTR2POLB | |
| SCHEMBL808041 | 0.61 | TRPV1 (0.39) | GAAADRA2AADRA2BADRA2C | |
| SCHEMBL13622605 | 0.61 | HCRTR1 (0.37) | KMT2AMEN1LMNAHCRTR1HCRTR2 | |
| SCHEMBL22235655 | 0.61 | TDP1 (0.57) | KMT2AMEN1LMNAMAPTHTT | |
| SCHEMBL367912 | 0.60 | L3MBTL1 (0.41) | HCRTR1HCRTR2 | |
| SCHEMBL17859342 | 0.60 | HCRTR2 (0.51) | LMNAHCRTR1HCRTR2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035023-A1 | TRIAZINE-OXADIAZOLES | NOVARTIS AG (CH) | 2012-03-22 | — | — | WO | disclosed |