Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 14/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | ATR | Q13535 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10287533 | 0.88 | ADRA2A (0.33) | ADRA2AADRA2BADRA2C | |
| SCHEMBL10287560 | 0.82 | HDAC4 (0.33) | TRPV1 | |
| SCHEMBL808249 | 0.75 | HDAC4 (0.30) | — | |
| SCHEMBL808244 | 0.74 | HDAC6 (0.34) | — | |
| SCHEMBL10287136 | 0.67 | ALDH1A1 (0.41) | GAA | |
| SCHEMBL795790 | 0.66 | AURKA (0.41) | TRPV1GAA | |
| SCHEMBL10287123 | 0.65 | POLB (0.41) | — | |
| SCHEMBL808315 | 0.64 | SMN1; SMN2 (0.39) | — | |
| SCHEMBL807957 | 0.63 | LMNA (0.41) | GAA | |
| SCHEMBL807959 | 0.61 | NPSR1 (0.33) | ADRA2AADRA2BADRA2CGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035023-A1 | TRIAZINE-OXADIAZOLES | NOVARTIS AG (CH) | 2012-03-22 | — | — | WO | disclosed |