SCHEMBL8079612

SCHEMBL8079612

CO[Si](CCCCNCCN(C)Cc1ccccc1)(OC)OC

nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.48
SIGMAR1 Q99720 7/20 0.47
TMEM97 Q5BJF2 4/20 0.47
TSHR P16473 1/20 0.45
APP P05067 2/20 0.43
CARM1 Q86X55 1/20 0.43
PRMT6 Q96LA8 1/20 0.43
PRMT8 Q9NR22 1/20 0.43
ACHE P22303 2/20 0.43
BCHE P06276 1/20 0.42
OPRM1 P35372 1/20 0.42
OPRK1 P41145 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20503703 0.96 SIGMAR1 (0.48) CHRM2SIGMAR1TMEM97TSHRAPP
SCHEMBL18419395 0.84 SIGMAR1 (0.56) SIGMAR1TSHRCARM1PRMT6PRMT8
SCHEMBL15966134 0.80 SIGMAR1 (0.60) CHRM2SIGMAR1TMEM97APPCARM1
SCHEMBL145173 0.79 ALDH1A1 (0.40) CHRM2SIGMAR1TMEM97
SCHEMBL28441746 0.79 OPRK1 (0.46) CHRM2SIGMAR1TSHROPRM1OPRK1
SCHEMBL8079615 0.79 SIGMAR1 (0.59) SIGMAR1OPRK1
SCHEMBL15966136 0.79 SIGMAR1 (0.58) CHRM2SIGMAR1TMEM97APPCARM1
SCHEMBL15966135 0.79 SIGMAR1 (0.58) CHRM2SIGMAR1TMEM97APPCARM1
SCHEMBL15966141 0.79 SIGMAR1 (0.58) CHRM2SIGMAR1TMEM97APPCARM1
SCHEMBL15966137 0.79 SIGMAR1 (0.58) CHRM2SIGMAR1TMEM97APPCARM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0702106-B1 Base fabric for air bags and method for the preparation thereof TAKATA CORP (JP) 2000-09-13 EP disclosed
US-5705445-A POLYSILOXANE TAKATA CORPORATION (JP) 1998-01-06 US disclosed
EP-0702106-A1 Base fabric for air bags and method for the preparation thereof TAKATA CORPORATION (JP) 1996-03-20 EP disclosed