Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 2/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CTSA | P10619 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8070679 | 0.83 | CREBBP (0.41) | CREBBPROCK2CYP1A2POLBHPGD | |
| SCHEMBL12712496 | 0.80 | BRD4 (0.38) | CREBBPROCK2FAAH | |
| SCHEMBL7826439 | 0.75 | FAAH (0.47) | CREBBPROCK2POLBFAAHALDH1A1 | |
| SCHEMBL7735556 | 0.71 | ALDH1A1 (0.51) | CREBBPROCK2FAAHHPGDALDH1A1 | |
| SCHEMBL9954382 | 0.70 | NPBWR1 (0.44) | CREBBPFAAH | |
| SCHEMBL8076929 | 0.69 | CREBBP (0.41) | CREBBPROCK2POLBALDH1A1MEN1 | |
| SCHEMBL9953430 | 0.69 | PTGS2 (0.43) | CREBBPROCK2ALDH1A1 | |
| SCHEMBL9954116 | 0.69 | PTGS2 (0.43) | CREBBPROCK2ALDH1A1 | |
| SCHEMBL9953264 | 0.69 | PTGS2 (0.43) | CREBBPROCK2ALDH1A1 | |
| SCHEMBL15305627 | 0.67 | PTGS2 (0.48) | CREBBPROCK2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009032277-A1 | GAMMA SECRETASE MODULATORS | SCHERING CORPORATION (US) | 2009-03-12 | — | — | WO | disclosed |