Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 20/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 19/20 | 0.44 |
| ▸ | ATR | Q13535 | 19/20 | 0.44 |
| ▸ | ATRIP | Q8WXE1 | 19/20 | 0.44 |
| ▸ | ATM | Q13315 | 11/20 | 0.44 |
| ▸ | MTOR | P42345 | 10/20 | 0.43 |
| ▸ | SERPINA2 | P20848 | 7/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15131797 | 0.86 | PIK3CB (0.42) | PRKDCPIK3CBATRATRIPATM | |
| SCHEMBL807973 | 0.85 | ATM (0.41) | PRKDCPIK3CBATRATRIPATM | |
| SCHEMBL807987 | 0.81 | GSK3B (0.38) | PRKDCPIK3CBATRATRIPATM | |
| SCHEMBL10070634 | 0.80 | MAPT (0.41) | PRKDCPIK3CBATRATRIPATM | |
| SCHEMBL807837 | 0.80 | PRKDC (0.38) | PRKDCPIK3CBATRATRIPATM | |
| SCHEMBL807826 | 0.74 | PI4KA (0.45) | PIK3CB | |
| SCHEMBL807839 | 0.73 | PRKDC (0.43) | PRKDCPIK3CBATRATRIPATM | |
| SCHEMBL15131796 | 0.73 | MTOR (0.49) | PRKDCPIK3CBATRATRIPATM | |
| SCHEMBL15131811 | 0.72 | MTOR (0.38) | PRKDCPIK3CBATRATRIPATM | |
| SCHEMBL10885012 | 0.72 | PRKDC (0.51) | PRKDCPIK3CBATRATRIPATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012034526-A1 | FUSED HETEROARYLS AND THEIR USES | HUTCHISON MEDIPHARMA LIMITED (CN) | 2012-03-22 | — | — | WO | disclosed |