Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 9/20 | 0.51 |
| ▸ | ATR | Q13535 | 9/20 | 0.51 |
| ▸ | ATRIP | Q8WXE1 | 9/20 | 0.51 |
| ▸ | PIK3CB | P42338 | 8/20 | 0.51 |
| ▸ | ATM | Q13315 | 7/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SERPINA2 | P20848 | 4/20 | 0.43 |
| ▸ | MTOR | P42345 | 4/20 | 0.43 |
| ▸ | PDE2A | O00408 | 3/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9036533 | 0.75 | ABL1 (0.44) | PRKDCATRATRIPPIK3CBATM | |
| SCHEMBL807975 | 0.72 | PRKDC (0.44) | PRKDCATRATRIPPIK3CBATM | |
| SCHEMBL807973 | 0.72 | ATM (0.41) | PRKDCATRATRIPPIK3CBATM | |
| SCHEMBL31612377 | 0.70 | ADORA3 (0.41) | PRKDCATRATRIPPIK3CBATM | |
| SCHEMBL15131806 | 0.70 | PIK3CB (0.47) | PRKDCATRATRIPPIK3CBATM | |
| SCHEMBL11868935 | 0.68 | ADORA3 (0.56) | PRKDCATRATRIPPIK3CBATM | |
| SCHEMBL5362675 | 0.68 | ADORA3 (0.43) | PRKDCATRATRIPPIK3CBATM | |
| SCHEMBL9081820 | 0.67 | MAPT (0.37) | PRKDCATRATRIPPIK3CBATM | |
| SCHEMBL10844794 | 0.66 | TYMS (0.74) | KDM4ERAB9APDE2APDE10A | |
| SCHEMBL1599017 | 0.66 | TYMS (0.39) | PRKDCATRATRIPPIK3CBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0107455-B1 | TRIAZOLOQUINOXALINES AS ANTIDEPRESSANTS AND ANTIFATIGUE AGENTS | PFIZER INC. (US) | 1986-07-09 | — | — | EP | disclosed |