Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.32 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PLK1 | P53350 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8071721 | 0.77 | SOAT2 (0.46) | SOAT2ACAT1SOAT1THRB | |
| SCHEMBL8071724 | 0.65 | SOAT2 (0.56) | SOAT2ACAT1SOAT1THRB | |
| SCHEMBL8041413 | 0.62 | SOAT1 (0.54) | SOAT2ACAT1SOAT1MAPTPLK1 | |
| SCHEMBL8080878 | 0.61 | SOAT2 (0.48) | GAATDP1L3MBTL1HPGDSOAT2 | |
| SCHEMBL11056444 | 0.57 | KMT2A (0.46) | GAAHPGD | |
| SCHEMBL8045136 | 0.57 | SOAT2 (0.56) | GAATDP1L3MBTL1HPGDSOAT2 | |
| SCHEMBL3519133 | 0.55 | HSD17B10 (0.47) | TDP1PPARAMAPTPOLBTHRB | |
| SCHEMBL9446337 | 0.54 | SOAT1 (0.53) | GAATDP1L3MBTL1HPGDSOAT2 | |
| SCHEMBL9446388 | 0.54 | SOAT1 (0.53) | GAATDP1L3MBTL1HPGDSOAT2 | |
| SCHEMBL9446369 | 0.54 | SOAT1 (0.53) | GAATDP1L3MBTL1HPGDSOAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871611-B1 | NEW DERIVATIVES OF GLYCYLANILIDES, PREPARATION AND THERAPEUTICAL APPLICATION | PF MEDICAMENT (FR) | 2000-09-13 | — | — | EP | claimed |