Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
| ▸ | TYMS | P04818 | 2/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8073164 | 0.92 | PIM1 (0.50) | PIM1CAMK2D | |
| SCHEMBL8065793 | 0.79 | CCNT1 (0.40) | CCNT1CDK9PIM1CAMK2D | |
| SCHEMBL8075637 | 0.73 | CCNT1 (0.50) | CCNT1CDK9PIM1CAMK2DSIRT2 | |
| SCHEMBL8074992 | 0.69 | PRKCA (0.63) | PIM1CAMK2D | |
| Hydrochloric Acid SCHEMBL8065191 | 0.69 | PRKCA (0.62) | PIM1CAMK2D | |
| SCHEMBL8166629 | 0.68 | PIM1 (0.59) | CCNT1CDK9PIM1CAMK2DSIRT2 | |
| SCHEMBL3155154 | 0.68 | CCNT1 (0.58) | CCNT1CDK9PIM1CAMK2D | |
| SCHEMBL8522346 | 0.67 | CCNE2 (0.56) | PIM1CAMK2D | |
| SCHEMBL8073176 | 0.67 | CCNT1 (0.47) | CCNT1CDK9PIM1CAMK2DSIRT2 | |
| SCHEMBL8161267 | 0.66 | CDK2 (0.56) | CCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153641-A | Pharmaceutically active compounds | ASTRA AKTIEBOLAG (SE) | 2000-11-28 | — | — | US | disclosed |