Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 8/20 | 0.78 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8079931 | 0.88 | SRD5A2 (1.00) | SRD5A2MAPTSMN1; SMN2HTTNPSR1 | |
| SCHEMBL8079992 | 0.78 | SRD5A2 (0.79) | SRD5A2MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL8080226 | 0.77 | SRD5A2 (0.74) | SRD5A2MEN1PKMKMT2AMAPT | |
| SCHEMBL8070861 | 0.76 | SRD5A2 (0.74) | SRD5A2MEN1PKMKMT2AMAPT | |
| SCHEMBL6225616 | 0.73 | ALDH1A1 (0.46) | SRD5A2MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL8070871 | 0.71 | SRD5A2 (0.64) | SRD5A2MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL8079953 | 0.70 | SRD5A2 (0.74) | SRD5A2MEN1PKMKMT2AFFAR1 | |
| SCHEMBL8083145 | 0.68 | SRD5A2 (0.79) | SRD5A2MEN1PKMKMT2AMAPT | |
| SCHEMBL8084624 | 0.66 | SRD5A2 (0.75) | SRD5A2MEN1PKMKMT2AFFAR1 | |
| SCHEMBL8078572 | 0.65 | SRD5A2 (0.77) | SRD5A2MEN1PKMKMT2AFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757982-B1 | Biphenylic compounds, process for their preparations and intermediates for this process, their use as 5-alpha-reductase inhibitors and pharmaceutical compositions containing them | HOECHST MARION ROUSSEL INC (FR) | 2000-09-20 | — | — | EP | claimed |