SCHEMBL8079998

SCHEMBL8079998

[C]c1ccc2c(c1)COC2

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.34
MAPT P10636 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
PRKCG P05129 1/20 0.32
PRKCA P17252 1/20 0.32
PRKCD Q05655 1/20 0.32
IKBKB O14920 1/20 0.32
CYP11B2 P19099 1/20 0.32
SYK P43405 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2761891 0.71 PRKCG (0.43) KDM4EMAPTL3MBTL1PRKCGPRKCA
SCHEMBL1362239 0.70 PNMT (0.42) MAPT
SCHEMBL29909954 0.70 MAPT (0.45) KDM4EMAPTL3MBTL1IKBKB
SCHEMBL3896106 0.70 IKBKB (0.41) KDM4EMAPTL3MBTL1IKBKB
SCHEMBL29417669 0.70 PNMT (0.42) MAPT
SCHEMBL30068612 0.70 HTR2A (0.45) KDM4EMAPTL3MBTL1
SCHEMBL892296 0.70 MAPT (0.45) KDM4EMAPTL3MBTL1IKBKB
SCHEMBL3218240 0.70 HTR2A (0.45) KDM4EMAPTL3MBTL1
SCHEMBL30743772 0.70 IKBKB (0.41) KDM4EMAPTL3MBTL1IKBKB
SCHEMBL59871 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1032566-A2 METHOD FOR THE PREPARATION OF CITALOPRAM H. LUNDBECK A/S (DK) 2000-09-06 EP disclosed
WO-1998019511-A2 METHOD FOR THE PREPARATION OF CITALOPRAM H. LUNDBECK A/S (DK) 1998-05-14 WO disclosed