Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 4/20 | 0.51 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.51 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.51 |
| ▸ | CDK2 | P24941 | 3/20 | 0.51 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.51 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 4/20 | 0.41 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.40 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.40 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.40 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.40 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.40 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.40 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11699945 | 0.82 | CDK1 (0.54) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL29308078 | 0.81 | CDK1 (0.53) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL2056438 | 0.76 | CCNA2 (0.67) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL19686248 | 0.74 | CDK1 (0.53) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL16516258 | 0.72 | LTA4H (0.53) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL20421683 | 0.71 | TLR8 (0.50) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL6398172 | 0.71 | CDK1 (0.40) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL11700870 | 0.71 | CDK1 (0.50) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| Water SCHEMBL13518273 | 0.70 | CDK1 (0.43) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL808604 | 0.70 | CDK1 (0.47) | CDK1CCNB1CCNA2CDK2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0522964-B1 | Compositions to arrest hair loss and to induce and stimulate hair growth based on 2,4-diamino-pyrimidin-3-oxide derivatives | OREAL (FR) | 2000-10-04 | — | — | EP | disclosed |
| US-5466694-A | Hair growth regulators | L'OREAL (FR) | 1995-11-14 | — | — | US | disclosed |
| EP-0522964-A1 | Compositions to arrest hair loss and to induce and stimulate hair growth based on 2,4-diamino-pyrimidin-3-oxide derivatives | L'OREAL (FR) | 1993-01-13 | — | — | EP | disclosed |