Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 4/20 | 0.53 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.53 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.53 |
| ▸ | CDK2 | P24941 | 3/20 | 0.53 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.53 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.53 |
| ▸ | TLR8 | Q9NR97 | 10/20 | 0.47 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.47 |
| ▸ | DHFR | P00374 | 2/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23114953 | 0.89 | CDK1 (0.49) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL29308078 | 0.86 | CDK1 (0.53) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL20421683 | 0.83 | TLR8 (0.50) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL23114952 | 0.81 | MAPK1 (0.41) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL12352016 | 0.79 | DHFR (0.49) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL11699945 | 0.76 | CDK1 (0.54) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL8080229 | 0.74 | CDK1 (0.51) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL20783723 | 0.73 | MPO (0.47) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL18049854 | 0.73 | NUDT1 (0.57) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL19146160 | 0.73 | CDK1 (0.36) | CDK1CCNB1CCNA2CDK2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210077634-A1 | IN VIVO PRODUCTION OF PROTEINS | MODERNATX INC (US) | 2021-03-18 | — | — | US | disclosed |
| US-20170348436-A1 | IN VIVO PRODUCTION OF PROTEINS | ARES CAPITAL CORPORATION, AS AGENT | 2017-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210077634-A1 | IN VIVO PRODUCTION OF PROTEINS | NSUN2, RNMT, NSUN3 | CDK1 1680/4885CCNB1 2416/4885CCNA2 1600/4885 |
| US-20170348436-A1 | IN VIVO PRODUCTION OF PROTEINS | MSH2, POLRMT, POLN | CDK1 3360/4885CCNB1 2615/4885CCNA2 1226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.