SCHEMBL8080243

SCHEMBL8080243

CCCCC(C)Oc1cc(CC(=O)O)cc(OC(C)CCCC)c1OC(C)CCCC

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
THRB P10828 9/20 0.50
THRA P10827 8/20 0.50
ALDH1A1 P00352 3/20 0.41
HPGD P15428 1/20 0.41
HSD17B10 Q99714 1/20 0.41
GAA P10253 1/20 0.37
TSHR P16473 1/20 0.37
NFKB1 P19838 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
PTPN1 P18031 1/20 0.36
PTPN6 P29350 1/20 0.36
PTPN11 Q06124 1/20 0.36
PDE4A P27815 3/20 0.36
PDE4B Q07343 3/20 0.36
PDE4C Q08493 3/20 0.36
PDE4D Q08499 3/20 0.36
GPR88 Q9GZN0 1/20 0.36
LNPEP Q9UIQ6 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8081329 0.96 THRB (0.51) THRBTHRAALDH1A1HPGDHSD17B10
SCHEMBL8081496 0.95 THRB (0.46) THRBTHRAALDH1A1HPGDHSD17B10
SCHEMBL8086395 0.94 THRB (0.52) THRBTHRAALDH1A1HPGDHSD17B10
SCHEMBL8080237 0.94 THRB (0.52) THRBTHRAALDH1A1HPGDHSD17B10
SCHEMBL8086437 0.91 THRB (0.47) THRBTHRAALDH1A1HPGDHSD17B10
SCHEMBL8081688 0.91 THRB (0.47) THRBTHRAALDH1A1HSD17B10GAA
SCHEMBL8082037 0.86 GAA (0.44) THRBTHRAALDH1A1HSD17B10GAA
SCHEMBL8086411 0.85 THRB (0.49) THRBTHRAALDH1A1HPGDHSD17B10
SCHEMBL8080294 0.84 ALDH1A1 (0.46) THRBTHRAALDH1A1HPGDHSD17B10
SCHEMBL8081214 0.82 PLA2G2A (0.42) THRBTHRAALDH1A1PDE4APDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0758013-B1 Liquid crystalline optical film, compensating film for liquid crystal display and liquid crystal display NIPPON OIL CO LTD (JP) 2000-10-11 EP disclosed
US-5855971-A Liquid crystalline optical film, compensating film for liquid crystal display comprising the liquid crystalline optical film, and liquid crystal display having the compensating film NIPPON OIL COMPANY, LIMITED (JP) 1999-01-05 US disclosed
EP-0758013-A1 Liquid crystalline optical film, compensating film for liquid crystal display and liquid crystal display NIPPON OIL COMPANY, LIMITED (JP) 1997-02-12 EP disclosed