SCHEMBL8080294

SCHEMBL8080294

CCCCC(C)Oc1ccc(CC(=O)O)cc1OC(C)CCCC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
HPGD P15428 1/20 0.46
HSD17B10 Q99714 1/20 0.46
GAA P10253 2/20 0.46
TSHR P16473 1/20 0.46
NFKB1 P19838 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
CA5A P35218 1/20 0.44
PTPN11 Q06124 2/20 0.43
PTPN1 P18031 1/20 0.43
PTPN6 P29350 1/20 0.43
PDE4A P27815 3/20 0.42
PDE4B Q07343 3/20 0.42
PDE4C Q08493 3/20 0.42
PDE4D Q08499 3/20 0.42
ALOX15 P16050 1/20 0.42
RXRA P19793 1/20 0.41
RXRB P28702 1/20 0.41
RXRG P48443 1/20 0.41
PPARG P37231 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8072266 0.96 ALDH1A1 (0.48) ALDH1A1HPGDHSD17B10GAATSHR
SCHEMBL8081661 0.92 ALDH1A1 (0.48) ALDH1A1HPGDHSD17B10GAATSHR
SCHEMBL8072663 0.85 GAA (0.50) ALDH1A1HPGDHSD17B10GAATSHR
SCHEMBL8080243 0.84 THRB (0.50) ALDH1A1HPGDHSD17B10GAATSHR
SCHEMBL8082104 0.81 ALDH1A1 (0.54) ALDH1A1HPGDHSD17B10PTPN11PDE4A
SCHEMBL8081329 0.81 THRB (0.51) ALDH1A1HPGDHSD17B10GAATSHR
SCHEMBL11577822 0.81 RXRA (0.58) ALDH1A1HPGDHSD17B10GAATSHR
SCHEMBL8081496 0.80 THRB (0.46) ALDH1A1HPGDHSD17B10GAATSHR
SCHEMBL8086395 0.80 THRB (0.52) ALDH1A1HPGDHSD17B10PTPN11PTPN1
SCHEMBL8080237 0.80 THRB (0.52) ALDH1A1HPGDHSD17B10PTPN11PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0758013-B1 Liquid crystalline optical film, compensating film for liquid crystal display and liquid crystal display NIPPON OIL CO LTD (JP) 2000-10-11 EP disclosed
US-5855971-A Liquid crystalline optical film, compensating film for liquid crystal display comprising the liquid crystalline optical film, and liquid crystal display having the compensating film NIPPON OIL COMPANY, LIMITED (JP) 1999-01-05 US disclosed
EP-0758013-A1 Liquid crystalline optical film, compensating film for liquid crystal display and liquid crystal display NIPPON OIL COMPANY, LIMITED (JP) 1997-02-12 EP disclosed