Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 16/20 | 0.44 |
| ▸ | PTGDR | Q13258 | 9/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8080971 | 0.71 | PTGIR (0.61) | PTGIRPTGDRPTGER3PTGER1CHRM4 | |
| SCHEMBL7776647 | 0.71 | PTGIR (0.64) | PTGIRPTGDRPTGER3PTGER1 | |
| SCHEMBL16964891 | 0.70 | TDP1 (0.59) | PTGIRPTGDRPTGER3PTGER1CHRM4 | |
| SCHEMBL8078053 | 0.68 | PTGIR (0.43) | PTGIRPTGDRPTGER3PTGER1CHRM4 | |
| SCHEMBL8082944 | 0.68 | PTGIR (0.63) | PTGIRPTGDRPTGER3PTGER1CHRM4 | |
| SCHEMBL16965819 | 0.67 | TDP1 (0.55) | PTGIRPTGDRPTGER3PTGER1CHRM4 | |
| SCHEMBL7779771 | 0.66 | PTGIR (0.46) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL8068504 | 0.66 | BLM (0.54) | PTGIRPTGDRPTGER3PTGER1CHRM4 | |
| SCHEMBL29233093 | 0.65 | LMNA (0.55) | PTGIRPTGDRCHRM4CHRM3CHRM5 | |
| SCHEMBL7772410 | 0.64 | SIGMAR1 (0.52) | PTGIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749424-A1 | NAPHTHALENE DERIVATIVES AS PROSTAGLANDIN I2 AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | EP | disclosed |